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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-315
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
4
4
1
Sequence
Reactive Loop
Linker
IA
CPLYC
LQVEYMTCLSSGDDKLPPRCNCCLAPKNCTLHLSDSTSIHCN
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-27
CPLYC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 27
Bond 2
7 - 15
Bond 3
29 - 48
Bond 4
30 - 36
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
I
A
C
P
L
Y
C
L
Q
V
E
Y
M
T
C
L
S
S
G
D
D
K
L
P
P
R
C
N
C
C
L
A
P
K
N
C
T
L
H
L
S
D
S
T
S
I
H
C
N
Amino Acid
Count
Percentage
Alanine
2
4.081632653
Cysteine
8
16.32653061
Aspartic acid
3
6.12244898
Glutamic acid
1
2.040816327
Phenylalanine
0
0
Glycine
1
2.040816327
Histidine
2
4.081632653
Isoleucine
2
4.081632653
Lysine
2
4.081632653
Leucine
7
14.28571429
Methionine
1
2.040816327
Asparagine
3
6.12244898
Proline
4
8.163265306
Glutamine
1
2.040816327
Arginine
1
2.040816327
Serine
5
10.20408163
Threonine
3
6.12244898
Valine
1
2.040816327
Tryptophan
0
0
Tyrosine
2
4.081632653