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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-413
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
1
4
1
Sequence
Reactive Loop
Linker
KA
CTLEC
DSRVAYMTCPSS
GLAKL
NQVCVNCCTAGEGCKLYGYDGSLICTG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-9
CTLEC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
L-71
GLAKL
20 - 24
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 31
Bond 2
7 - 32
Bond 3
16 - 28
Bond 4
38 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
K
A
C
T
L
E
C
D
S
R
V
A
Y
M
T
C
P
S
S
G
L
A
K
L
N
Q
V
C
V
N
C
C
T
A
G
E
G
C
K
L
Y
G
Y
D
G
S
L
I
C
T
G
Amino Acid
Count
Percentage
Alanine
4
7.843137255
Cysteine
8
15.68627451
Aspartic acid
2
3.921568627
Glutamic acid
2
3.921568627
Phenylalanine
0
0
Glycine
6
11.76470588
Histidine
0
0
Isoleucine
1
1.960784314
Lysine
3
5.882352941
Leucine
5
9.803921569
Methionine
1
1.960784314
Asparagine
2
3.921568627
Proline
1
1.960784314
Glutamine
1
1.960784314
Arginine
1
1.960784314
Serine
4
7.843137255
Threonine
4
7.843137255
Valine
3
5.882352941
Tryptophan
0
0
Tyrosine
3
5.882352941