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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-512
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
1
4
1
Sequence
Reactive Loop
Linker
KP
CPRNC
DPRIAYAICPHS
KISNK
IDLSGICTNCCAGKKGCYYFSVDGTFICEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
L-64
KISNK
20 - 24
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 34
Bond 2
7 - 35
Bond 3
16 - 31
Bond 4
41 - 52
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
K
P
C
P
R
N
C
D
P
R
I
A
Y
A
I
C
P
H
S
K
I
S
N
K
I
D
L
S
G
I
C
T
N
C
C
A
G
K
K
G
C
Y
Y
F
S
V
D
G
T
F
I
C
E
G
Amino Acid
Count
Percentage
Alanine
3
5.555555556
Cysteine
8
14.81481481
Aspartic acid
3
5.555555556
Glutamic acid
1
1.851851852
Phenylalanine
2
3.703703704
Glycine
5
9.259259259
Histidine
1
1.851851852
Isoleucine
6
11.11111111
Lysine
5
9.259259259
Leucine
1
1.851851852
Methionine
0
0
Asparagine
3
5.555555556
Proline
4
7.407407407
Glutamine
0
0
Arginine
2
3.703703704
Serine
4
7.407407407
Threonine
2
3.703703704
Valine
1
1.851851852
Tryptophan
0
0
Tyrosine
3
5.555555556