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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-11
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
TGCTTCCTGYKGCYYFGKDGKFVCEGESTEPKA
CTLEC
DPRVAYMTCPSA
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-9
CTLEC
34 - 38
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 38
Bond 2
6 - 24
Bond 3
7 - 34
Bond 4
13 - 47
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
D
G
K
F
V
C
E
G
E
S
T
E
P
K
A
C
T
L
E
C
D
P
R
V
A
Y
M
T
C
P
S
A
Amino Acid
Count
Percentage
Alanine
3
6
Cysteine
8
16
Aspartic acid
2
4
Glutamic acid
4
8
Phenylalanine
2
4
Glycine
6
12
Histidine
0
0
Isoleucine
0
0
Lysine
4
8
Leucine
1
2
Methionine
1
2
Asparagine
0
0
Proline
3
6
Glutamine
0
0
Arginine
1
2
Serine
2
4
Threonine
7
14
Valine
2
4
Tryptophan
0
0
Tyrosine
4
8