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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-116
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H-L Type (Type-I)
1
4
1
Sequence
Reactive Loop
Linker
RLCPNCCAGRKGCNYYSADGTFICEGES
DPNNP
KA
CPRNC
DPNYCYLLPIH
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
36 - 40
Trypsin
Linkers
Entry
Linker
Position
Type
L-5
DPNNP
29 - 33
Type-I(DPRNP)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 36
Bond 2
6 - 40
Bond 3
7 - 24
Bond 4
13 - 45
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
R
L
C
P
N
C
C
A
G
R
K
G
C
N
Y
Y
S
A
D
G
T
F
I
C
E
G
E
S
D
P
N
N
P
K
A
C
P
R
N
C
D
P
N
Y
C
Y
L
L
P
I
H
Amino Acid
Count
Percentage
Alanine
3
5.882352941
Cysteine
8
15.68627451
Aspartic acid
3
5.882352941
Glutamic acid
2
3.921568627
Phenylalanine
1
1.960784314
Glycine
4
7.843137255
Histidine
1
1.960784314
Isoleucine
2
3.921568627
Lysine
2
3.921568627
Leucine
3
5.882352941
Methionine
0
0
Asparagine
6
11.76470588
Proline
6
11.76470588
Glutamine
0
0
Arginine
3
5.882352941
Serine
2
3.921568627
Threonine
1
1.960784314
Valine
0
0
Tryptophan
0
0
Tyrosine
4
7.843137255