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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-120
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H-L Type (Type-I)
1
2
1
Sequence
Reactive Loop
Linker
AVQAVRVATNYSADGTFICEGES
DPNNP
KA
CPRNC
DQILPIHCVS
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
31 - 35
Trypsin
Linkers
Entry
Linker
Position
Type
L-5
DPNNP
24 - 28
Type-I(DPRNP)
Disulphide Bonds
Bond No.
Position
Bond 1
19 - 43
Bond 2
31 - 35
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
A
V
Q
A
V
R
V
A
T
N
Y
S
A
D
G
T
F
I
C
E
G
E
S
D
P
N
N
P
K
A
C
P
R
N
C
D
Q
I
L
P
I
H
C
V
S
Amino Acid
Count
Percentage
Alanine
5
11.11111111
Cysteine
4
8.888888889
Aspartic acid
3
6.666666667
Glutamic acid
2
4.444444444
Phenylalanine
1
2.222222222
Glycine
2
4.444444444
Histidine
1
2.222222222
Isoleucine
3
6.666666667
Lysine
1
2.222222222
Leucine
1
2.222222222
Methionine
0
0
Asparagine
4
8.888888889
Proline
4
8.888888889
Glutamine
2
4.444444444
Arginine
2
4.444444444
Serine
3
6.666666667
Threonine
2
4.444444444
Valine
4
8.888888889
Tryptophan
0
0
Tyrosine
1
2.222222222