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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-173
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H-L Type (Type-I)
1
4
1
Sequence
Reactive Loop
Linker
RICTNCCAGTKGCNYFSADGTFVCEGES
DPRNP
KA
CPRNC
DGRIAYGVCPRS
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
36 - 40
Trypsin
Linkers
Entry
Linker
Position
Type
L-1
DPRNP
29 - 33
Type-I(DPRNP)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 40
Bond 2
6 - 24
Bond 3
7 - 36
Bond 4
13 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
R
I
C
T
N
C
C
A
G
T
K
G
C
N
Y
F
S
A
D
G
T
F
V
C
E
G
E
S
D
P
R
N
P
K
A
C
P
R
N
C
D
G
R
I
A
Y
G
V
C
P
R
S
Amino Acid
Count
Percentage
Alanine
4
7.692307692
Cysteine
8
15.38461538
Aspartic acid
3
5.769230769
Glutamic acid
2
3.846153846
Phenylalanine
2
3.846153846
Glycine
6
11.53846154
Histidine
0
0
Isoleucine
2
3.846153846
Lysine
2
3.846153846
Leucine
0
0
Methionine
0
0
Asparagine
4
7.692307692
Proline
4
7.692307692
Glutamine
0
0
Arginine
5
9.615384615
Serine
3
5.769230769
Threonine
3
5.769230769
Valine
2
3.846153846
Tryptophan
0
0
Tyrosine
2
3.846153846