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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-18
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
GLCTNCCAGKKGCKYFSKDGTYICDGESEWVSEKNNNLKKA
CTKEC
DTRIDFGICPLL
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-10
CTKEC
42 - 46
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 46
Bond 2
6 - 24
Bond 3
7 - 42
Bond 4
13 - 55
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
G
L
C
T
N
C
C
A
G
K
K
G
C
K
Y
F
S
K
D
G
T
Y
I
C
D
G
E
S
E
W
V
S
E
K
N
N
N
L
K
K
A
C
T
K
E
C
D
T
R
I
D
F
G
I
C
P
L
L
Amino Acid
Count
Percentage
Alanine
2
3.448275862
Cysteine
8
13.79310345
Aspartic acid
4
6.896551724
Glutamic acid
4
6.896551724
Phenylalanine
2
3.448275862
Glycine
6
10.34482759
Histidine
0
0
Isoleucine
3
5.172413793
Lysine
8
13.79310345
Leucine
4
6.896551724
Methionine
0
0
Asparagine
4
6.896551724
Proline
1
1.724137931
Glutamine
0
0
Arginine
1
1.724137931
Serine
3
5.172413793
Threonine
4
6.896551724
Valine
1
1.724137931
Tryptophan
1
1.724137931
Tyrosine
2
3.448275862