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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-2
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
QICTNCCAGKKGCMYFSDDGTFICEGESEYVSEVPVDNKP
CPRNC
DGRIAYGICPLS
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
41 - 45
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 45
Bond 2
6 - 24
Bond 3
7 - 41
Bond 4
13 - 54
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
Q
I
C
T
N
C
C
A
G
K
K
G
C
M
Y
F
S
D
D
G
T
F
I
C
E
G
E
S
E
Y
V
S
E
V
P
V
D
N
K
P
C
P
R
N
C
D
G
R
I
A
Y
G
I
C
P
L
S
Amino Acid
Count
Percentage
Alanine
2
3.50877193
Cysteine
8
14.03508772
Aspartic acid
4
7.01754386
Glutamic acid
4
7.01754386
Phenylalanine
2
3.50877193
Glycine
6
10.52631579
Histidine
0
0
Isoleucine
4
7.01754386
Lysine
3
5.263157895
Leucine
1
1.754385965
Methionine
1
1.754385965
Asparagine
3
5.263157895
Proline
4
7.01754386
Glutamine
1
1.754385965
Arginine
2
3.50877193
Serine
4
7.01754386
Threonine
2
3.50877193
Valine
3
5.263157895
Tryptophan
0
0
Tyrosine
3
5.263157895