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Domains (IRDs)
Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-26
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
PLCVNCCSGKIGCKYFNKNGTFICDGGSEWDGRKA
CSKEC
DPRIDIGFCAYV
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-13
CSKEC
36 - 40
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 40
Bond 2
6 - 24
Bond 3
7 - 36
Bond 4
13 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
P
L
C
V
N
C
C
S
G
K
I
G
C
K
Y
F
N
K
N
G
T
F
I
C
D
G
G
S
E
W
D
G
R
K
A
C
S
K
E
C
D
P
R
I
D
I
G
F
C
A
Y
V
Amino Acid
Count
Percentage
Alanine
2
3.846153846
Cysteine
8
15.38461538
Aspartic acid
4
7.692307692
Glutamic acid
2
3.846153846
Phenylalanine
3
5.769230769
Glycine
7
13.46153846
Histidine
0
0
Isoleucine
4
7.692307692
Lysine
5
9.615384615
Leucine
1
1.923076923
Methionine
0
0
Asparagine
3
5.769230769
Proline
2
3.846153846
Glutamine
0
0
Arginine
2
3.846153846
Serine
3
5.769230769
Threonine
1
1.923076923
Valine
2
3.846153846
Tryptophan
1
1.923076923
Tyrosine
2
3.846153846