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Reactive Loops (RCL)
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Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-289
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
KG
CSRNC
DTEVDYMVCPSGGETITRNVCTNCCSAQKSCKLFRSDGSVKCSG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-22
CSRNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 28
Bond 2
7 - 32
Bond 3
16 - 38
Bond 4
31 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
K
G
C
S
R
N
C
D
T
E
V
D
Y
M
V
C
P
S
G
G
E
T
I
T
R
N
V
C
T
N
C
C
S
A
Q
K
S
C
K
L
F
R
S
D
G
S
V
K
C
S
G
Amino Acid
Count
Percentage
Alanine
1
1.960784314
Cysteine
8
15.68627451
Aspartic acid
3
5.882352941
Glutamic acid
2
3.921568627
Phenylalanine
1
1.960784314
Glycine
5
9.803921569
Histidine
0
0
Isoleucine
1
1.960784314
Lysine
4
7.843137255
Leucine
1
1.960784314
Methionine
1
1.960784314
Asparagine
3
5.882352941
Proline
1
1.960784314
Glutamine
1
1.960784314
Arginine
3
5.882352941
Serine
7
13.7254902
Threonine
4
7.843137255
Valine
4
7.843137255
Tryptophan
0
0
Tyrosine
1
1.960784314