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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-296
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
1
4
1
Sequence
Reactive Loop
Linker
NI
CTQHC
DPRVAYSKCPRS
GGNTI
IKHTECTTCCTGYKGCYYFGHDGKFVCEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-25
CTQHC
3 - 7
Unknown
Linkers
Entry
Linker
Position
Type
L-72
GGNTI
20 - 24
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 33
Bond 2
7 - 34
Bond 3
16 - 30
Bond 4
40 - 51
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
N
I
C
T
Q
H
C
D
P
R
V
A
Y
S
K
C
P
R
S
G
G
N
T
I
I
K
H
T
E
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
H
D
G
K
F
V
C
E
G
Amino Acid
Count
Percentage
Alanine
1
1.886792453
Cysteine
8
15.09433962
Aspartic acid
2
3.773584906
Glutamic acid
2
3.773584906
Phenylalanine
2
3.773584906
Glycine
7
13.20754717
Histidine
3
5.660377358
Isoleucine
3
5.660377358
Lysine
4
7.547169811
Leucine
0
0
Methionine
0
0
Asparagine
2
3.773584906
Proline
2
3.773584906
Glutamine
1
1.886792453
Arginine
2
3.773584906
Serine
2
3.773584906
Threonine
6
11.32075472
Valine
2
3.773584906
Tryptophan
0
0
Tyrosine
4
7.547169811