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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-301
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
KA
CPLYC
LDVDYMTCESSGDKKLNSACNCCLAPKNCTLHLADGRMVQC
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-27
CPLYC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 30
Bond 2
7 - 36
Bond 3
15 - 48
Bond 4
27 - 29
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
K
A
C
P
L
Y
C
L
D
V
D
Y
M
T
C
E
S
S
G
D
K
K
L
N
S
A
C
N
C
C
L
A
P
K
N
C
T
L
H
L
A
D
G
R
M
V
Q
C
Amino Acid
Count
Percentage
Alanine
4
8.333333333
Cysteine
8
16.66666667
Aspartic acid
4
8.333333333
Glutamic acid
1
2.083333333
Phenylalanine
0
0
Glycine
2
4.166666667
Histidine
1
2.083333333
Isoleucine
0
0
Lysine
4
8.333333333
Leucine
6
12.5
Methionine
2
4.166666667
Asparagine
3
6.25
Proline
2
4.166666667
Glutamine
1
2.083333333
Arginine
1
2.083333333
Serine
3
6.25
Threonine
2
4.166666667
Valine
2
4.166666667
Tryptophan
0
0
Tyrosine
2
4.166666667