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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-306
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
EA
CPLYC
LDVEYMTCESSGEEKLSPRCNCCLAPKNCTLHLSDGTSIFCK
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-27
CPLYC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 27
Bond 2
7 - 30
Bond 3
15 - 36
Bond 4
29 - 48
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
E
A
C
P
L
Y
C
L
D
V
E
Y
M
T
C
E
S
S
G
E
E
K
L
S
P
R
C
N
C
C
L
A
P
K
N
C
T
L
H
L
S
D
G
T
S
I
F
C
K
Amino Acid
Count
Percentage
Alanine
2
4.081632653
Cysteine
8
16.32653061
Aspartic acid
2
4.081632653
Glutamic acid
5
10.20408163
Phenylalanine
1
2.040816327
Glycine
2
4.081632653
Histidine
1
2.040816327
Isoleucine
1
2.040816327
Lysine
3
6.12244898
Leucine
6
12.24489796
Methionine
1
2.040816327
Asparagine
2
4.081632653
Proline
3
6.12244898
Glutamine
0
0
Arginine
1
2.040816327
Serine
5
10.20408163
Threonine
3
6.12244898
Valine
1
2.040816327
Tryptophan
0
0
Tyrosine
2
4.081632653