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Reactive Loops (RCL)
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Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-308
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
KA
CPLYC
LDVDYMTCVSSGEEKLTAPCNCCLAPKQCTLHLVDGSEVQCD
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-27
CPLYC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 30
Bond 2
7 - 36
Bond 3
15 - 48
Bond 4
27 - 29
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
K
A
C
P
L
Y
C
L
D
V
D
Y
M
T
C
V
S
S
G
E
E
K
L
T
A
P
C
N
C
C
L
A
P
K
Q
C
T
L
H
L
V
D
G
S
E
V
Q
C
D
Amino Acid
Count
Percentage
Alanine
3
6.12244898
Cysteine
8
16.32653061
Aspartic acid
4
8.163265306
Glutamic acid
3
6.12244898
Phenylalanine
0
0
Glycine
2
4.081632653
Histidine
1
2.040816327
Isoleucine
0
0
Lysine
3
6.12244898
Leucine
6
12.24489796
Methionine
1
2.040816327
Asparagine
1
2.040816327
Proline
3
6.12244898
Glutamine
2
4.081632653
Arginine
0
0
Serine
3
6.12244898
Threonine
3
6.12244898
Valine
4
8.163265306
Tryptophan
0
0
Tyrosine
2
4.081632653