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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-339
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
RF
CPLFC
FRSEYMTCPSTGYERLPPQCNCCLAGPGCKIYGFDGRLLCAE
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-35
CPLFC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 30
Bond 2
7 - 36
Bond 3
15 - 47
Bond 4
27 - 29
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
R
F
C
P
L
F
C
F
R
S
E
Y
M
T
C
P
S
T
G
Y
E
R
L
P
P
Q
C
N
C
C
L
A
G
P
G
C
K
I
Y
G
F
D
G
R
L
L
C
A
E
Amino Acid
Count
Percentage
Alanine
2
4.081632653
Cysteine
8
16.32653061
Aspartic acid
1
2.040816327
Glutamic acid
3
6.12244898
Phenylalanine
4
8.163265306
Glycine
5
10.20408163
Histidine
0
0
Isoleucine
1
2.040816327
Lysine
1
2.040816327
Leucine
5
10.20408163
Methionine
1
2.040816327
Asparagine
1
2.040816327
Proline
5
10.20408163
Glutamine
1
2.040816327
Arginine
4
8.163265306
Serine
2
4.081632653
Threonine
2
4.081632653
Valine
0
0
Tryptophan
0
0
Tyrosine
3
6.12244898