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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-357
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
2
4
2
Sequence
Reactive Loop
Linker
KV
CNKIC
YGAAAYMTCPSSGSTQLDPVCNCCLAPALGCTLYESDGTPICTS
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-42
CNKIC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 28
Bond 2
7 - 31
Bond 3
16 - 38
Bond 4
30 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
K
V
C
N
K
I
C
Y
G
A
A
A
Y
M
T
C
P
S
S
G
S
T
Q
L
D
P
V
C
N
C
C
L
A
P
A
L
G
C
T
L
Y
E
S
D
G
T
P
I
C
T
S
Amino Acid
Count
Percentage
Alanine
5
9.803921569
Cysteine
8
15.68627451
Aspartic acid
2
3.921568627
Glutamic acid
1
1.960784314
Phenylalanine
0
0
Glycine
4
7.843137255
Histidine
0
0
Isoleucine
2
3.921568627
Lysine
2
3.921568627
Leucine
4
7.843137255
Methionine
1
1.960784314
Asparagine
2
3.921568627
Proline
4
7.843137255
Glutamine
1
1.960784314
Arginine
0
0
Serine
5
9.803921569
Threonine
5
9.803921569
Valine
2
3.921568627
Tryptophan
0
0
Tyrosine
3
5.882352941