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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-37
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
TGCTNCCTGYKGCYYFGKDGKFVCEGESTEPKK
CPAIC
IIAAYMTCPSS
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-21
CPAIC
34 - 38
Elastase
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 38
Bond 2
6 - 24
Bond 3
7 - 34
Bond 4
13 - 46
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
T
G
C
T
N
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
D
G
K
F
V
C
E
G
E
S
T
E
P
K
K
C
P
A
I
C
I
I
A
A
Y
M
T
C
P
S
S
Amino Acid
Count
Percentage
Alanine
3
6.12244898
Cysteine
8
16.32653061
Aspartic acid
1
2.040816327
Glutamic acid
3
6.12244898
Phenylalanine
2
4.081632653
Glycine
6
12.24489796
Histidine
0
0
Isoleucine
3
6.12244898
Lysine
5
10.20408163
Leucine
0
0
Methionine
1
2.040816327
Asparagine
1
2.040816327
Proline
3
6.12244898
Glutamine
0
0
Arginine
0
0
Serine
3
6.12244898
Threonine
5
10.20408163
Valine
1
2.040816327
Tryptophan
0
0
Tyrosine
4
8.163265306