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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-39
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
VGCTNCCAAKKGCNYFSANGTFVCKGESVVESMIEAVKP
CRRNC
DGRISYSVCGNK
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-32
CRRNC
40 - 44
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 44
Bond 2
6 - 24
Bond 3
7 - 40
Bond 4
13 - 53
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
V
G
C
T
N
C
C
A
A
K
K
G
C
N
Y
F
S
A
N
G
T
F
V
C
K
G
E
S
V
V
E
S
M
I
E
A
V
K
P
C
R
R
N
C
D
G
R
I
S
Y
S
V
C
G
N
K
Amino Acid
Count
Percentage
Alanine
4
7.142857143
Cysteine
8
14.28571429
Aspartic acid
1
1.785714286
Glutamic acid
3
5.357142857
Phenylalanine
2
3.571428571
Glycine
6
10.71428571
Histidine
0
0
Isoleucine
2
3.571428571
Lysine
5
8.928571429
Leucine
0
0
Methionine
1
1.785714286
Asparagine
5
8.928571429
Proline
1
1.785714286
Glutamine
0
0
Arginine
3
5.357142857
Serine
5
8.928571429
Threonine
2
3.571428571
Valine
6
10.71428571
Tryptophan
0
0
Tyrosine
2
3.571428571