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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Proteins (PIs)
Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-392
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
AA
CPQFC
LDVAYVTCPSSGSEQLPARCNCCMTPAGCTLHLSDGTQQTC
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-12
CPQFC
3 - 7
Unknown
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 27
Bond 2
7 - 30
Bond 3
15 - 36
Bond 4
29 - 48
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
A
A
C
P
Q
F
C
L
D
V
A
Y
V
T
C
P
S
S
G
S
E
Q
L
P
A
R
C
N
C
C
M
T
P
A
G
C
T
L
H
L
S
D
G
T
Q
Q
T
C
Amino Acid
Count
Percentage
Alanine
5
10.41666667
Cysteine
8
16.66666667
Aspartic acid
2
4.166666667
Glutamic acid
1
2.083333333
Phenylalanine
1
2.083333333
Glycine
3
6.25
Histidine
1
2.083333333
Isoleucine
0
0
Lysine
0
0
Leucine
4
8.333333333
Methionine
1
2.083333333
Asparagine
1
2.083333333
Proline
4
8.333333333
Glutamine
4
8.333333333
Arginine
1
2.083333333
Serine
4
8.333333333
Threonine
5
10.41666667
Valine
2
4.166666667
Tryptophan
0
0
Tyrosine
1
2.083333333