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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-418
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
2
4
1
Sequence
Reactive Loop
Linker
KG
CTKEC
DPRVAYMTCPSS
GLAKL
NQVCVNCCSAGEGCKLYDNDGSLLCTG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-10
CTKEC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
L-71
GLAKL
20 - 24
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 31
Bond 2
7 - 32
Bond 3
16 - 28
Bond 4
38 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
K
G
C
T
K
E
C
D
P
R
V
A
Y
M
T
C
P
S
S
G
L
A
K
L
N
Q
V
C
V
N
C
C
S
A
G
E
G
C
K
L
Y
D
N
D
G
S
L
L
C
T
G
Amino Acid
Count
Percentage
Alanine
3
5.882352941
Cysteine
8
15.68627451
Aspartic acid
3
5.882352941
Glutamic acid
2
3.921568627
Phenylalanine
0
0
Glycine
6
11.76470588
Histidine
0
0
Isoleucine
0
0
Lysine
4
7.843137255
Leucine
5
9.803921569
Methionine
1
1.960784314
Asparagine
3
5.882352941
Proline
2
3.921568627
Glutamine
1
1.960784314
Arginine
1
1.960784314
Serine
4
7.843137255
Threonine
3
5.882352941
Valine
3
5.882352941
Tryptophan
0
0
Tyrosine
2
3.921568627