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Reactive Loops (RCL)
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Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-426
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
1
4
1
Sequence
Reactive Loop
Linker
NT
CPKNC
DSKIAYSKCLLS
EGNRV
IENIECTSCCTGYKGCYYFGLDGKFVCEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-11
CPKNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
L-77
EGNRV
20 - 24
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 33
Bond 2
7 - 34
Bond 3
16 - 30
Bond 4
40 - 51
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
N
T
C
P
K
N
C
D
S
K
I
A
Y
S
K
C
L
L
S
E
G
N
R
V
I
E
N
I
E
C
T
S
C
C
T
G
Y
K
G
C
Y
Y
F
G
L
D
G
K
F
V
C
E
G
Amino Acid
Count
Percentage
Alanine
1
1.886792453
Cysteine
8
15.09433962
Aspartic acid
2
3.773584906
Glutamic acid
4
7.547169811
Phenylalanine
2
3.773584906
Glycine
6
11.32075472
Histidine
0
0
Isoleucine
3
5.660377358
Lysine
5
9.433962264
Leucine
3
5.660377358
Methionine
0
0
Asparagine
4
7.547169811
Proline
1
1.886792453
Glutamine
0
0
Arginine
1
1.886792453
Serine
4
7.547169811
Threonine
3
5.660377358
Valine
2
3.773584906
Tryptophan
0
0
Tyrosine
4
7.547169811