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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-435
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
2
4
2
Sequence
Reactive Loop
Linker
KP
CRRNC
DGRISYSVCGNKKSSGRICTNCCAGKKGCNYFSADGTFVCEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-32
CRRNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 26
Bond 2
7 - 30
Bond 3
16 - 36
Bond 4
29 - 47
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
K
P
C
R
R
N
C
D
G
R
I
S
Y
S
V
C
G
N
K
K
S
S
G
R
I
C
T
N
C
C
A
G
K
K
G
C
N
Y
F
S
A
D
G
T
F
V
C
E
G
Amino Acid
Count
Percentage
Alanine
2
4.081632653
Cysteine
8
16.32653061
Aspartic acid
2
4.081632653
Glutamic acid
1
2.040816327
Phenylalanine
2
4.081632653
Glycine
7
14.28571429
Histidine
0
0
Isoleucine
2
4.081632653
Lysine
5
10.20408163
Leucine
0
0
Methionine
0
0
Asparagine
4
8.163265306
Proline
1
2.040816327
Glutamine
0
0
Arginine
4
8.163265306
Serine
5
10.20408163
Threonine
2
4.081632653
Valine
2
4.081632653
Tryptophan
0
0
Tyrosine
2
4.081632653