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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-439
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
AG
CPRNC
DPDAAYIKCPPNPKKTEAGCTNCCVSTSRGCRLYYSNNTRLC
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 27
Bond 2
7 - 31
Bond 3
16 - 38
Bond 4
30 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
A
G
C
P
R
N
C
D
P
D
A
A
Y
I
K
C
P
P
N
P
K
K
T
E
A
G
C
T
N
C
C
V
S
T
S
R
G
C
R
L
Y
Y
S
N
N
T
R
L
C
Amino Acid
Count
Percentage
Alanine
4
8.163265306
Cysteine
8
16.32653061
Aspartic acid
2
4.081632653
Glutamic acid
1
2.040816327
Phenylalanine
0
0
Glycine
3
6.12244898
Histidine
0
0
Isoleucine
1
2.040816327
Lysine
3
6.12244898
Leucine
2
4.081632653
Methionine
0
0
Asparagine
5
10.20408163
Proline
5
10.20408163
Glutamine
0
0
Arginine
4
8.163265306
Serine
3
6.12244898
Threonine
4
8.163265306
Valine
1
2.040816327
Tryptophan
0
0
Tyrosine
3
6.12244898