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Reactive Loops (RCL)
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Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-464
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
2
4
1
Sequence
Reactive Loop
Linker
KA
CTLEC
GNLGYGICPRS
EGSPE
NPICTNCCAGYKGCNYYSANGTFICEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-9
CTLEC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
L-47
EGSPE
19 - 23
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 27
Bond 2
7 - 31
Bond 3
15 - 37
Bond 4
30 - 48
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
K
A
C
T
L
E
C
G
N
L
G
Y
G
I
C
P
R
S
E
G
S
P
E
N
P
I
C
T
N
C
C
A
G
Y
K
G
C
N
Y
Y
S
A
N
G
T
F
I
C
E
G
Amino Acid
Count
Percentage
Alanine
3
6
Cysteine
8
16
Aspartic acid
0
0
Glutamic acid
4
8
Phenylalanine
1
2
Glycine
8
16
Histidine
0
0
Isoleucine
3
6
Lysine
2
4
Leucine
2
4
Methionine
0
0
Asparagine
5
10
Proline
3
6
Glutamine
0
0
Arginine
1
2
Serine
3
6
Threonine
3
6
Valine
0
0
Tryptophan
0
0
Tyrosine
4
8