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Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-490
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
3
1
Sequence
Reactive Loop
Linker
NV
CPRNC
DTNIAYLKCLRSEGKSLVYPAGCTTCCTGYKGGYYFGKNGKFVCEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 34
Bond 2
7 - 33
Bond 3
16 - 51
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
N
V
C
P
R
N
C
D
T
N
I
A
Y
L
K
C
L
R
S
E
G
K
S
L
V
Y
P
A
G
C
T
T
C
C
T
G
Y
K
G
G
Y
Y
F
G
K
N
G
K
F
V
C
E
G
Amino Acid
Count
Percentage
Alanine
2
3.773584906
Cysteine
7
13.20754717
Aspartic acid
1
1.886792453
Glutamic acid
2
3.773584906
Phenylalanine
2
3.773584906
Glycine
8
15.09433962
Histidine
0
0
Isoleucine
1
1.886792453
Lysine
5
9.433962264
Leucine
3
5.660377358
Methionine
0
0
Asparagine
4
7.547169811
Proline
2
3.773584906
Glutamine
0
0
Arginine
2
3.773584906
Serine
2
3.773584906
Threonine
4
7.547169811
Valine
3
5.660377358
Tryptophan
0
0
Tyrosine
5
9.433962264