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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-500
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
2
4
1
Sequence
Reactive Loop
Linker
KA
CPLNC
DTNIAYSRCPRSEGKSLIYPTGCTTCCTGYKDCYYFDKNGKFVCEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-2
CPLNC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 33
Bond 2
7 - 34
Bond 3
16 - 30
Bond 4
40 - 51
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
K
A
C
P
L
N
C
D
T
N
I
A
Y
S
R
C
P
R
S
E
G
K
S
L
I
Y
P
T
G
C
T
T
C
C
T
G
Y
K
D
C
Y
Y
F
D
K
N
G
K
F
V
C
E
G
Amino Acid
Count
Percentage
Alanine
2
3.773584906
Cysteine
8
15.09433962
Aspartic acid
3
5.660377358
Glutamic acid
2
3.773584906
Phenylalanine
2
3.773584906
Glycine
5
9.433962264
Histidine
0
0
Isoleucine
2
3.773584906
Lysine
5
9.433962264
Leucine
2
3.773584906
Methionine
0
0
Asparagine
3
5.660377358
Proline
3
5.660377358
Glutamine
0
0
Arginine
2
3.773584906
Serine
3
5.660377358
Threonine
5
9.433962264
Valine
1
1.886792453
Tryptophan
0
0
Tyrosine
5
9.433962264