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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-5
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
2
1
Sequence
Reactive Loop
Linker
LGCTNCCAGSLGCNYYSANGTFICEGESEIKVETIETEVETMVEPNKI
CPRNC
DPKIRYG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
49 - 53
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
7 - 49
Bond 2
24 - 53
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
L
G
C
T
N
C
C
A
G
S
L
G
C
N
Y
Y
S
A
N
G
T
F
I
C
E
G
E
S
E
I
K
V
E
T
I
E
T
E
V
E
T
M
V
E
P
N
K
I
C
P
R
N
C
D
P
K
I
R
Y
G
Amino Acid
Count
Percentage
Alanine
2
3.333333333
Cysteine
7
11.66666667
Aspartic acid
1
1.666666667
Glutamic acid
8
13.33333333
Phenylalanine
1
1.666666667
Glycine
6
10
Histidine
0
0
Isoleucine
5
8.333333333
Lysine
3
5
Leucine
2
3.333333333
Methionine
1
1.666666667
Asparagine
5
8.333333333
Proline
3
5
Glutamine
0
0
Arginine
2
3.333333333
Serine
3
5
Threonine
5
8.333333333
Valine
3
5
Tryptophan
0
0
Tyrosine
3
5