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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-506
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
1
4
1
Sequence
Reactive Loop
Linker
KH
CLGNC
DPKIAYSKCPGRS
EGKTI
IKPTGCTTCCTGYKGCYYYGKDGKFVCEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-47
CLGNC
3 - 7
Elastase
Linkers
Entry
Linker
Position
Type
L-75
EGKTI
21 - 25
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 34
Bond 2
7 - 35
Bond 3
16 - 31
Bond 4
41 - 52
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
K
H
C
L
G
N
C
D
P
K
I
A
Y
S
K
C
P
G
R
S
E
G
K
T
I
I
K
P
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
Y
G
K
D
G
K
F
V
C
E
G
Amino Acid
Count
Percentage
Alanine
1
1.851851852
Cysteine
8
14.81481481
Aspartic acid
2
3.703703704
Glutamic acid
2
3.703703704
Phenylalanine
1
1.851851852
Glycine
9
16.66666667
Histidine
1
1.851851852
Isoleucine
3
5.555555556
Lysine
8
14.81481481
Leucine
1
1.851851852
Methionine
0
0
Asparagine
1
1.851851852
Proline
3
5.555555556
Glutamine
0
0
Arginine
1
1.851851852
Serine
2
3.703703704
Threonine
5
9.259259259
Valine
1
1.851851852
Tryptophan
0
0
Tyrosine
5
9.259259259