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Reactive Loops (RCL)
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Reactive Loops (RCL)
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Domain Details
Domain List
IRD-619
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
L-H Type (Type-II)
4
4
2
Sequence
Reactive Loop
Linker
KA
CPRNC
DERIAYGICPRT
EEKKN
NQICTNCCAGTKGCNYFSANGTFICEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
L-25
EEKKN
20 - 24
Type-II(EEKKN)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 28
Bond 2
7 - 32
Bond 3
16 - 38
Bond 4
31 - 49
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
K
A
C
P
R
N
C
D
E
R
I
A
Y
G
I
C
P
R
T
E
E
K
K
N
N
Q
I
C
T
N
C
C
A
G
T
K
G
C
N
Y
F
S
A
N
G
T
F
I
C
E
G
Amino Acid
Count
Percentage
Alanine
4
7.843137255
Cysteine
8
15.68627451
Aspartic acid
1
1.960784314
Glutamic acid
4
7.843137255
Phenylalanine
2
3.921568627
Glycine
5
9.803921569
Histidine
0
0
Isoleucine
4
7.843137255
Lysine
4
7.843137255
Leucine
0
0
Methionine
0
0
Asparagine
6
11.76470588
Proline
2
3.921568627
Glutamine
1
1.960784314
Arginine
3
5.882352941
Serine
1
1.960784314
Threonine
4
7.843137255
Valine
0
0
Tryptophan
0
0
Tyrosine
2
3.921568627