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Domains (IRDs)
Reactive Loops (RCL)
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Target Protease
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-677
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
MA
CPLYC
LDVEYMTCNGTKVTPGRCNCCLAPKGCILHLSDGTSVNCG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-27
CPLYC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 25
Bond 2
7 - 15
Bond 3
27 - 46
Bond 4
28 - 34
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
M
A
C
P
L
Y
C
L
D
V
E
Y
M
T
C
N
G
T
K
V
T
P
G
R
C
N
C
C
L
A
P
K
G
C
I
L
H
L
S
D
G
T
S
V
N
C
G
Amino Acid
Count
Percentage
Alanine
2
4.255319149
Cysteine
8
17.0212766
Aspartic acid
2
4.255319149
Glutamic acid
1
2.127659574
Phenylalanine
0
0
Glycine
5
10.63829787
Histidine
1
2.127659574
Isoleucine
1
2.127659574
Lysine
2
4.255319149
Leucine
5
10.63829787
Methionine
2
4.255319149
Asparagine
3
6.382978723
Proline
3
6.382978723
Glutamine
0
0
Arginine
1
2.127659574
Serine
2
4.255319149
Threonine
4
8.510638298
Valine
3
6.382978723
Tryptophan
0
0
Tyrosine
2
4.255319149