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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
IRD-684
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
2
1
Sequence
Reactive Loop
Linker
RP
CPLIC
HPPKIKVCPSRGTNRIPISVLPPDKEPSNGCHLYNLKTGAP
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-39
CPLIC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 7
Bond 2
15 - 38
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
R
P
C
P
L
I
C
H
P
P
K
I
K
V
C
P
S
R
G
T
N
R
I
P
I
S
V
L
P
P
D
K
E
P
S
N
G
C
H
L
Y
N
L
K
T
G
A
P
Amino Acid
Count
Percentage
Alanine
1
2.083333333
Cysteine
4
8.333333333
Aspartic acid
1
2.083333333
Glutamic acid
1
2.083333333
Phenylalanine
0
0
Glycine
3
6.25
Histidine
2
4.166666667
Isoleucine
4
8.333333333
Lysine
4
8.333333333
Leucine
4
8.333333333
Methionine
0
0
Asparagine
3
6.25
Proline
10
20.83333333
Glutamine
0
0
Arginine
3
6.25
Serine
3
6.25
Threonine
2
4.166666667
Valine
2
4.166666667
Tryptophan
0
0
Tyrosine
1
2.083333333