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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
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Domain Details
Domain List
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
4
1
Sequence
Reactive Loop
Linker
KV
CPLVC
FKAAYMICPHPPHKKLRPVCNCCLAKPHCKLYRHDGTVICTA
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-41
CPLVC
3 - 7
Chymotrypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 27
Bond 2
7 - 30
Bond 3
15 - 36
Bond 4
29 - 47
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
K
V
C
P
L
V
C
F
K
A
A
Y
M
I
C
P
H
P
P
H
K
K
L
R
P
V
C
N
C
C
L
A
K
P
H
C
K
L
Y
R
H
D
G
T
V
I
C
T
A
Amino Acid
Count
Percentage
Alanine
4
8.163265306
Cysteine
8
16.32653061
Aspartic acid
1
2.040816327
Glutamic acid
0
0
Phenylalanine
1
2.040816327
Glycine
1
2.040816327
Histidine
4
8.163265306
Isoleucine
2
4.081632653
Lysine
6
12.24489796
Leucine
4
8.163265306
Methionine
1
2.040816327
Asparagine
1
2.040816327
Proline
6
12.24489796
Glutamine
0
0
Arginine
2
4.081632653
Serine
0
0
Threonine
2
4.081632653
Valine
4
8.163265306
Tryptophan
0
0
Tyrosine
2
4.081632653