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Reactive Loops (RCL)
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Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-693
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H+L Type (Type-III)
1
0
1
Sequence
Reactive Loop
Linker
KA
CPRNC
DTRIAYSKMSTFRRKTQKIAYAPIAVQAVRVATNYSADGTFICEG
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
3 - 7
Trypsin
Linkers
Entry
Linker
Position
Type
Disulphide Bonds
Bond No.
Position
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
K
A
C
P
R
N
C
D
T
R
I
A
Y
S
K
M
S
T
F
R
R
K
T
Q
K
I
A
Y
A
P
I
A
V
Q
A
V
R
V
A
T
N
Y
S
A
D
G
T
F
I
C
E
G
Amino Acid
Count
Percentage
Alanine
8
15.38461538
Cysteine
3
5.769230769
Aspartic acid
2
3.846153846
Glutamic acid
1
1.923076923
Phenylalanine
2
3.846153846
Glycine
2
3.846153846
Histidine
0
0
Isoleucine
4
7.692307692
Lysine
4
7.692307692
Leucine
0
0
Methionine
1
1.923076923
Asparagine
2
3.846153846
Proline
2
3.846153846
Glutamine
2
3.846153846
Arginine
5
9.615384615
Serine
3
5.769230769
Threonine
5
9.615384615
Valine
3
5.769230769
Tryptophan
0
0
Tyrosine
3
5.769230769