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Reactive Loops (RCL)
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Domains (IRDs)
Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-70
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H-L Type (Type-I)
1
4
1
Sequence
Reactive Loop
Linker
PICTTCCAGYKGCKYYNANGTFICEGQS
DPRKP
NEH
CPKEC
NRKIAYSKCPHS
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-23
CPKEC
37 - 41
Trypsin
Linkers
Entry
Linker
Position
Type
L-16
DPRKP
29 - 33
Type-I(DPRNP)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 41
Bond 2
6 - 24
Bond 3
7 - 37
Bond 4
13 - 50
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
P
I
C
T
T
C
C
A
G
Y
K
G
C
K
Y
Y
N
A
N
G
T
F
I
C
E
G
Q
S
D
P
R
K
P
N
E
H
C
P
K
E
C
N
R
K
I
A
Y
S
K
C
P
H
S
Amino Acid
Count
Percentage
Alanine
3
5.660377358
Cysteine
8
15.09433962
Aspartic acid
1
1.886792453
Glutamic acid
3
5.660377358
Phenylalanine
1
1.886792453
Glycine
4
7.547169811
Histidine
2
3.773584906
Isoleucine
3
5.660377358
Lysine
6
11.32075472
Leucine
0
0
Methionine
0
0
Asparagine
4
7.547169811
Proline
5
9.433962264
Glutamine
1
1.886792453
Arginine
2
3.773584906
Serine
3
5.660377358
Threonine
3
5.660377358
Valine
0
0
Tryptophan
0
0
Tyrosine
4
7.547169811