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Reactive Loops (RCL)
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Reactive Loops (RCL)
Linkers
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Domain Details
Domain List
IRD-76
Overview
RCL/Linker
Disulphide Bonds
Amino acid (aa) Composition
Domain Type
No. Of PIs
No. of DS Bonds
No. of Species
H-L Type (Type-I)
2
3
1
Sequence
Reactive Loop
Linker
QICTNCCAGIKGCNYFSVDGTFVCEGES
DPRNS
KA
CPRNC
DPRYALIVAQ
REACTIVE LOOPS
Entry
RCL
Position
Target Protease
RL-1
CPRNC
36 - 40
Trypsin
Linkers
Entry
Linker
Position
Type
L-4
DPRNS
29 - 33
Type-I(DPRNP)
Disulphide Bonds
Bond No.
Position
Bond 1
3 - 24
Bond 2
7 - 13
Bond 3
36 - 40
Architecture
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
Q
I
C
T
N
C
C
A
G
I
K
G
C
N
Y
F
S
V
D
G
T
F
V
C
E
G
E
S
D
P
R
N
S
K
A
C
P
R
N
C
D
P
R
Y
A
L
I
V
A
Q
Amino Acid
Count
Percentage
Alanine
4
8
Cysteine
7
14
Aspartic acid
3
6
Glutamic acid
2
4
Phenylalanine
2
4
Glycine
4
8
Histidine
0
0
Isoleucine
3
6
Lysine
2
4
Leucine
1
2
Methionine
0
0
Asparagine
4
8
Proline
3
6
Glutamine
2
4
Arginine
3
6
Serine
3
6
Threonine
2
4
Valine
3
6
Tryptophan
0
0
Tyrosine
2
4