Home
Browse
Proteins (PIs)
Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
Taxonomy
Domain Architecture
Data Analysis
Proteins (PIs)
Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
Search
Downloads
Contact Us
Proteins
Proteins (PIs)
Proteins details
PINIR_101
[
I3QHF0
] :
Proteinase inhibitor II
148
Length
Solanum lycopersicum
Specie
-
Gene Name
16308
Mass
3
Domain Count
Overview
Function
Domains
Amino acid (aa) Composition
Visualization
Sequence :
FASTA Sequence copied to clipboard!
×
FASTA
MAVQQEVNFV
AYLLIVHGMF
LYVDAKACTR
ECGNLGFGIC
PRSEGSPLNP
ICINCCSGYK
GCNYYNSFGK
70
FICEGESDPK
RPNACTFNCD
PNIAYSRCPR
SQGKSLIYPT
GCTTCCTGYK
GCYYFGKDGK
FVCEGESDEP
140
KANMYPVM
148
SIGNAL PEPTIDE
SEQUENCE
Position
MAVQQEVNFVAYLLIVHGMFLYVDA
1 ↔ 25
DISULPHIDE BOND
Disulfidebondtype
Position
Disulfide bond 1
3 ↔ 27
Disulfide bond 1
3 ↔ 33
Disulfide bond 1
3 ↔ 40
Disulfide bond 2
6 ↔ 24
Disulfide bond 2
7 ↔ 31
Disulfide bond 2
7 ↔ 34
Disulfide bond 3
7 ↔ 36
Disulfide bond 3
15 ↔ 37
Disulfide bond 3
16 ↔ 30
Disulfide bond 4
13 ↔ 49
Disulfide bond 4
30 ↔ 48
Disulfide bond 4
40 ↔ 51
DOMAINS ARCHITECTURE
View diagram
Domain
Position
Length
Architecture
IRD-62
50 - 101
52
IRD-405
83 - 135
53
IRD-456
26 - 75
50
ISO - ELECTRIC POINT
Iso Eelectric Point
charge at pH 7.4
charge at pH 5.5
charge at pH 8.0
6.624
2.2
-5.8
-11.6
CROSS REFERENCES
Uniprot
Interpro Id
Pfam Id
EMBL
I3QHF0
View PI in InterPro
IPR003465
View protein in Pfam
PF02428
JN132112
REFERENCES
PubMed ID:
Application:
REACTIVE LOOPS
Entry
RCL Sequence
Target Protease
Position
RL-4
CTREC
Trypsin
29 - 33
RL-7
CTFNC
Chymotrypsin
86 - 90
RL-7
CTFNC
Chymotrypsin
86 - 90
GO TERMS
Molecular Function
Cellular Component
Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867)
None
None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution
Induction
Elicitor Molecules
Target Insect
Remarks
Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM)
IC50 (uM)
Target Protease
Cross Reactivity
Remarks
Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity
Binding Energy
Stability
Remarks
Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers
Alpha Helix Numbers
Coil Numbers
Disulphide Bonds Numbers
Remarks
Reference
No Records Found
Entry
Domain Position
RCL
RCL Position
Linker
Linker Position
Domain Type
IRD-62
50 - 101
CTFNC
85 - 89
DPKRP
78 - 82
H-L Type (Type-I)
IRD-405
83 - 135
CTFNC
85 - 89
-
H+L Type (Type-III)
IRD-456
26 - 75
CTREC
28 - 32
EGSPL
44 - 48
L-H Type (Type-II)
Domain(
IRD-62
)
:
PICINCCSGYKGCNYYNSFGKFICEGES
DPKRP
NA
CTFNC
DPNIAYSRCPRS
Reactive Loop(RCL)
:
CTFNC
Linker
:
DPKRP
Domain Type
:
H-L Type (Type-I)
Disulphide Bond
:
3,40 ; 6,24 ; 7,36 ; 13,49
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
P
I
C
I
N
C
C
S
G
Y
K
G
C
N
Y
Y
N
S
F
G
K
F
I
C
E
G
E
S
D
P
K
R
P
N
A
C
T
F
N
C
D
P
N
I
A
Y
S
R
C
P
R
S
Domain(
IRD-405
)
:
NA
CTFNC
DPNIAYSRCPRSQGKSLIYPTGCTTCCTGYKGCYYFGKDGKFVCEG
Reactive Loop(RCL)
:
CTFNC
Linker
:
Domain Type
:
H+L Type (Type-III)
Disulphide Bond
:
3,33 ; 7,34 ; 16,30 ; 40,51
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
N
A
C
T
F
N
C
D
P
N
I
A
Y
S
R
C
P
R
S
Q
G
K
S
L
I
Y
P
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
D
G
K
F
V
C
E
G
Domain(
IRD-456
)
:
KA
CTREC
GNLGFGICPRS
EGSPL
NPICINCCSGYKGCNYYNSFGKFICEG
Reactive Loop(RCL)
:
CTREC
Linker
:
EGSPL
Domain Type
:
L-H Type (Type-II)
Disulphide Bond
:
3,27 ; 7,31 ; 15,37 ; 30,48
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
K
A
C
T
R
E
C
G
N
L
G
F
G
I
C
P
R
S
E
G
S
P
L
N
P
I
C
I
N
C
C
S
G
Y
K
G
C
N
Y
Y
N
S
F
G
K
F
I
C
E
G
DOMAINS ARCHITECTURE
Domain
Position
Length
Architecture
IRD-62
50 - 101
52
IRD-405
83 - 135
53
IRD-456
26 - 75
50
Amino Acid
Count
% by Frequency
Alanine
7
4.73
Cysteine
16
10.81
Aspartic acid
5
3.38
Glutamic acid
8
5.41
Phenylalanine
8
5.41
Glycine
16
10.81
Histidine
1
0.68
Isoleucine
7
4.73
Lysine
9
6.08
Leucine
6
4.05
Methionine
4
2.7
Asparagine
10
6.76
Proline
10
6.76
Glutamine
3
2.03
Arginine
5
3.38
Serine
9
6.08
Threonine
6
4.05
Valine
7
4.73
Tryptophan
0
0
Tyrosine
11
7.43
Architecture
×
Signal Peptide
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
M
A
V
Q
Q
E
V
N
F
V
A
Y
L
L
I
V
H
G
M
F
L
Y
V
D
A
K
A
C
T
R
E
C
G
N
L
G
F
G
I
C
P
R
S
E
G
S
P
L
N
P
I
C
I
N
C
C
S
G
Y
K
G
C
N
Y
Y
N
S
F
G
K
F
I
C
E
G
E
S
D
P
K
R
P
N
A
C
T
F
N
C
D
P
N
I
A
Y
S
R
C
P
R
S
Q
G
K
S
L
I
Y
P
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
D
G
K
F
V
C
E
G
E
S
D
E
P
K
A
N
M
Y
P
V
M
A
V
Q
Q
E
V
N
F
V
A
Y
L
L
I
V
H
G
M
F
L
Y
V
D
A
K
Domains
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
M
A
V
Q
Q
E
V
N
F
V
A
Y
L
L
I
V
H
G
M
F
L
Y
V
D
A
K
A
C
T
R
E
C
G
N
L
G
F
G
I
C
P
R
S
E
G
S
P
L
N
P
I
C
I
N
C
C
S
G
Y
K
G
C
N
Y
Y
N
S
F
G
K
F
I
C
E
G
E
S
D
P
K
R
P
N
A
C
T
F
N
C
D
P
N
I
A
Y
S
R
C
P
R
S
Q
G
K
S
L
I
Y
P
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
D
G
K
F
V
C
E
G
E
S
D
E
P
K
A
N
M
Y
P
V
M
