Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_11 [Q43652]  : Proteinase inhibitor type-2 CM7 (Proteinase inhibitor type II CM7)

154Length

Solanum tuberosumSpecie

PIN2-CM7Gene Name

16868Mass

3Domain Count

Sequence :
     FASTA
MDVHKEVNFV AYLLIVLGIF LLVSVVEHVD AKICTKECGN LGFGICPRSE GSPKNPICIN CCSGYKGCNY 70
YSVFGRFICE GESDLKNPKA CPLNCDTNIA YSRCPHSEGK SLIYPTGCTT CCTGYKGCYY FGKNGKFVCE 140
GESDEPKANM YPAM 154
SIGNAL PEPTIDE
SEQUENCE Position
MDVHKEVNFVAYLLIVLGIFLLVSVVEHVDA
 1 ↔ 31
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-16
32 - 81 50
IRD-59
56 - 107 52
IRD-497
89 - 141 53
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
6.36299999999999
2.5 -6.8 -12.8
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
Q43652 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 X78275
REFERENCES
PubMed ID:     7846166    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-10 CTKEC Trypsin 35 - 39
RL-2 CPLNC Chymotrypsin 92 - 96
RL-2 CPLNC Chymotrypsin 92 - 96
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
Gene structure 7846166
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
Trypsin, chymotrypsin 7846166
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-16 32 - 81 CTKEC 34 - 38 EGSPK 50 - 54 L-H Type (Type-II)
IRD-59 56 - 107 CPLNC 91 - 95 DLKNP 84 - 88 H-L Type (Type-I)
IRD-497 89 - 141 CPLNC 91 - 95 - H+L Type (Type-III)
KICTKECGNLGFGICPRSEGSPKNPICINCCSGYKGCNYYSVFGRFICEG
CTKEC
EGSPK
L-H Type (Type-II)
3,27 ; 7,31 ; 15,37 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K I C T K E C G N L G F G I C P R S E G S P K N P I C I N C C S G Y K G C N Y Y S V F G R F I C E G


PICINCCSGYKGCNYYSVFGRFICEGESDLKNPKACPLNCDTNIAYSRCPHS
CPLNC
DLKNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C I N C C S G Y K G C N Y Y S V F G R F I C E G E S D L K N P K A C P L N C D T N I A Y S R C P H S


KACPLNCDTNIAYSRCPHSEGKSLIYPTGCTTCCTGYKGCYYFGKNGKFVCEG
CPLNC
H+L Type (Type-III)
3,33 ; 7,34 ; 16,30 ; 40,51
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
K A C P L N C D T N I A Y S R C P H S E G K S L I Y P T G C T T C C T G Y K G C Y Y F G K N G K F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-16
 32 - 81 50
IRD-59
 56 - 107 52
IRD-497
 89 - 141 53
Amino Acid Count % by Frequency
Alanine 6 3.9
Cysteine 16 10.39
Aspartic acid 5 3.25
Glutamic acid 10 6.49
Phenylalanine 7 4.55
Glycine 16 10.39
Histidine 3 1.95
Isoleucine 9 5.84
Lysine 12 7.79
Leucine 9 5.84
Methionine 3 1.95
Asparagine 10 6.49
Proline 9 5.84
Glutamine 0 0
Arginine 3 1.95
Serine 10 6.49
Threonine 6 3.9
Valine 10 6.49
Tryptophan 0 0
Tyrosine 10 6.49