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Proteins
Proteins (PIs)
Proteins details
PINIR_170
[
Q84L56
] :
Proteinase inhibitor 2 protein (Proteinase inhibitor II protein)
154
Length
Solanum phureja
Specie
PIN-II2x Pin-II2x
Gene Name
16641
Mass
3
Domain Count
Overview
Function
Domains
Amino acid (aa) Composition
Visualization
Sequence :
FASTA Sequence copied to clipboard!
×
FASTA
MAVHKEVNFV
AYLLIVLGLL
VLVSAMEHVD
AKACTLECGN
LGFGICPRSE
GSPENRICTN
CCAGYKGCNY
70
YSANGAFICE
GESDPKNPNV
CPRNCDTNIA
YSKCPRSEGK
SLIYPTGCTT
CCTGYKGCYY
FGKNGKFVCE
140
GESDEPKANM
YPAM
154
SIGNAL PEPTIDE
SEQUENCE
Position
MAVHKEVNFVAYLLIVLGLLVLVSA
1 ↔ 25
DISULPHIDE BOND
Disulfidebondtype
Position
Disulfide bond 1
3 ↔ 27
Disulfide bond 1
3 ↔ 33
Disulfide bond 1
3 ↔ 40
Disulfide bond 2
6 ↔ 24
Disulfide bond 2
7 ↔ 31
Disulfide bond 2
7 ↔ 34
Disulfide bond 3
7 ↔ 36
Disulfide bond 3
15 ↔ 37
Disulfide bond 3
16 ↔ 30
Disulfide bond 4
13 ↔ 49
Disulfide bond 4
30 ↔ 48
Disulfide bond 4
40 ↔ 51
DOMAINS ARCHITECTURE
View diagram
Domain
Position
Length
Architecture
IRD-236
56 - 107
52
IRD-467
32 - 81
50
IRD-487
89 - 141
53
ISO - ELECTRIC POINT
Iso Eelectric Point
charge at pH 7.4
charge at pH 5.5
charge at pH 8.0
5.777
0.9
-7.8
-13.7
CROSS REFERENCES
Uniprot
Interpro Id
Pfam Id
EMBL
Q84L56
View PI in InterPro
IPR003465
View protein in Pfam
PF02428
AY247794
AY517498
REFERENCES
PubMed ID:
Application:
REACTIVE LOOPS
Entry
RCL Sequence
Target Protease
Position
RL-1
CPRNC
Trypsin
92 - 96
RL-1
CPRNC
Trypsin
92 - 96
RL-9
CTLEC
Chymotrypsin
35 - 39
GO TERMS
Molecular Function
Cellular Component
Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867)
None
None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution
Induction
Elicitor Molecules
Target Insect
Remarks
Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM)
IC50 (uM)
Target Protease
Cross Reactivity
Remarks
Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity
Binding Energy
Stability
Remarks
Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers
Alpha Helix Numbers
Coil Numbers
Disulphide Bonds Numbers
Remarks
Reference
No Records Found
Entry
Domain Position
RCL
RCL Position
Linker
Linker Position
Domain Type
IRD-236
56 - 107
CPRNC
91 - 95
DPKNP
84 - 88
H-L Type (Type-I)
IRD-467
32 - 81
CTLEC
34 - 38
EGSPE
50 - 54
L-H Type (Type-II)
IRD-487
89 - 141
CPRNC
91 - 95
-
H+L Type (Type-III)
Domain(
IRD-236
)
:
RICTNCCAGYKGCNYYSANGAFICEGES
DPKNP
NV
CPRNC
DTNIAYSKCPRS
Reactive Loop(RCL)
:
CPRNC
Linker
:
DPKNP
Domain Type
:
H-L Type (Type-I)
Disulphide Bond
:
3,40 ; 6,24 ; 7,36 ; 13,49
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
R
I
C
T
N
C
C
A
G
Y
K
G
C
N
Y
Y
S
A
N
G
A
F
I
C
E
G
E
S
D
P
K
N
P
N
V
C
P
R
N
C
D
T
N
I
A
Y
S
K
C
P
R
S
Domain(
IRD-467
)
:
KA
CTLEC
GNLGFGICPRS
EGSPE
NRICTNCCAGYKGCNYYSANGAFICEG
Reactive Loop(RCL)
:
CTLEC
Linker
:
EGSPE
Domain Type
:
L-H Type (Type-II)
Disulphide Bond
:
3,27 ; 7,31 ; 15,37 ; 30,48
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
K
A
C
T
L
E
C
G
N
L
G
F
G
I
C
P
R
S
E
G
S
P
E
N
R
I
C
T
N
C
C
A
G
Y
K
G
C
N
Y
Y
S
A
N
G
A
F
I
C
E
G
Domain(
IRD-487
)
:
NV
CPRNC
DTNIAYSKCPRSEGKSLIYPTGCTTCCTGYKGCYYFGKNGKFVCEG
Reactive Loop(RCL)
:
CPRNC
Linker
:
Domain Type
:
H+L Type (Type-III)
Disulphide Bond
:
3,33 ; 7,34 ; 16,30 ; 40,51
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
N
V
C
P
R
N
C
D
T
N
I
A
Y
S
K
C
P
R
S
E
G
K
S
L
I
Y
P
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
N
G
K
F
V
C
E
G
DOMAINS ARCHITECTURE
Domain
Position
Length
Architecture
IRD-236
56 - 107
52
IRD-467
32 - 81
50
IRD-487
89 - 141
53
Amino Acid
Count
% by Frequency
Alanine
11
7.14
Cysteine
16
10.39
Aspartic acid
4
2.6
Glutamic acid
11
7.14
Phenylalanine
5
3.25
Glycine
16
10.39
Histidine
2
1.3
Isoleucine
6
3.9
Lysine
10
6.49
Leucine
9
5.84
Methionine
4
2.6
Asparagine
12
7.79
Proline
9
5.84
Glutamine
0
0
Arginine
4
2.6
Serine
9
5.84
Threonine
7
4.55
Valine
9
5.84
Tryptophan
0
0
Tyrosine
10
6.49
Architecture
×
Signal Peptide
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
M
A
V
H
K
E
V
N
F
V
A
Y
L
L
I
V
L
G
L
L
V
L
V
S
A
M
E
H
V
D
A
K
A
C
T
L
E
C
G
N
L
G
F
G
I
C
P
R
S
E
G
S
P
E
N
R
I
C
T
N
C
C
A
G
Y
K
G
C
N
Y
Y
S
A
N
G
A
F
I
C
E
G
E
S
D
P
K
N
P
N
V
C
P
R
N
C
D
T
N
I
A
Y
S
K
C
P
R
S
E
G
K
S
L
I
Y
P
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
N
G
K
F
V
C
E
G
E
S
D
E
P
K
A
N
M
Y
P
A
M
A
V
H
K
E
V
N
F
V
A
Y
L
L
I
V
L
G
L
L
V
L
V
S
A
M
Domains
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
M
A
V
H
K
E
V
N
F
V
A
Y
L
L
I
V
L
G
L
L
V
L
V
S
A
M
E
H
V
D
A
K
A
C
T
L
E
C
G
N
L
G
F
G
I
C
P
R
S
E
G
S
P
E
N
R
I
C
T
N
C
C
A
G
Y
K
G
C
N
Y
Y
S
A
N
G
A
F
I
C
E
G
E
S
D
P
K
N
P
N
V
C
P
R
N
C
D
T
N
I
A
Y
S
K
C
P
R
S
E
G
K
S
L
I
Y
P
T
G
C
T
T
C
C
T
G
Y
K
G
C
Y
Y
F
G
K
N
G
K
F
V
C
E
G
E
S
D
E
P
K
A
N
M
Y
P
A
M
