Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_176 [Q7M222]  : Probable proteinase inhibitor

146Length

Solanum lycopersicumSpecie

101255652Gene Name

15637Mass

3Domain Count

Sequence :
     FASTA
MAFNKVALLI LFAIFAGTVL LLSEVDAANA CPRNCNPSIQ YGRCPKSGNK KFKVGCTNCC SGTEGCNYYS 70
ANGTFICEGQ TKKTIDETNK ACPRNCNPRI AYSICPGNKR SEGRICTNCC AGSKGCNYYT VDGTFVCEGE 140
SKVDSS 146
SIGNAL PEPTIDE
SEQUENCE Position
MAFNKVALLILFAIFAGTVLLLSEVDA
 1 ↔ 27
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-4
54 - 108 55
IRD-483
90 - 139 50
IRD-524
29 - 79 51
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
7.496
6.5 -0.8 -6.8
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
Q7M222 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428
REFERENCES
PubMed ID:     8804387    | 22660326    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 32 - 36
RL-1 CPRNC Trypsin 93 - 97
RL-1 CPRNC Trypsin 93 - 97
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
Genome annotation 22660326
shoot; flower 8804387
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-4 54 - 108 CPRNC 92 - 96 - H+L Type (Type-III)
IRD-483 90 - 139 CPRNC 92 - 96 - H+L Type (Type-III)
IRD-524 29 - 79 CPRNC 31 - 35 GNKKF 48 - 52 L-H Type (Type-II)
VGCTNCCSGTEGCNYYSANGTFICEGQTKKTIDETNKACPRNCNPRIAYSICPGN
CPRNC
H+L Type (Type-III)
3,43 ; 6,24 ; 7,39 ; 13,52
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
V G C T N C C S G T E G C N Y Y S A N G T F I C E G Q T K K T I D E T N K A C P R N C N P R I A Y S I C P G N


KACPRNCNPRIAYSICPGNKRSEGRICTNCCAGSKGCNYYTVDGTFVCEG
CPRNC
H+L Type (Type-III)
3,27 ; 7,31 ; 16,37 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K A C P R N C N P R I A Y S I C P G N K R S E G R I C T N C C A G S K G C N Y Y T V D G T F V C E G


NACPRNCNPSIQYGRCPKSGNKKFKVGCTNCCSGTEGCNYYSANGTFICEG
CPRNC
GNKKF
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
N A C P R N C N P S I Q Y G R C P K S G N K K F K V G C T N C C S G T E G C N Y Y S A N G T F I C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-4
 54 - 108 55
IRD-483
 90 - 139 50
IRD-524
 29 - 79 51
Amino Acid Count % by Frequency
Alanine 11 7.53
Cysteine 16 10.96
Aspartic acid 4 2.74
Glutamic acid 7 4.79
Phenylalanine 6 4.11
Glycine 14 9.59
Histidine 0 0
Isoleucine 8 5.48
Lysine 11 7.53
Leucine 6 4.11
Methionine 1 0.68
Asparagine 14 9.59
Proline 6 4.11
Glutamine 2 1.37
Arginine 6 4.11
Serine 11 7.53
Threonine 10 6.85
Valine 7 4.79
Tryptophan 0 0
Tyrosine 6 4.11