Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_20 [A0A1S3YTB5]  : proteinase inhibitor type-2 CEVI57-like

160Length

Nicotiana tabacumSpecie

LOC107779503Gene Name

17480Mass

1Domain Count

Sequence :
     FASTA
MKGVGIGAVL ISETGHHYPV TTQLRFYCTN NMAEYEACIL GPRLAVDMGI QEVLVLGDSY LLLKRITSSN 70
QRIQRKMAFY KASILSLLLL SGIFLLGIGE VKYVNAKSCL QFCDNEVAYM TCPSSGDEQI SPVCVNCCTA 140
DEGCKLFRTD GSLICTGTQD 160
SIGNAL PEPTIDE
SEQUENCE Position
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-346
107 - 157 51
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
5.35
-0.2 -6.2 -10
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
A0A1S3YTB5 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428
REFERENCES
PubMed ID:     24807620    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-37 CLQFC Unknown 110 - 114
GO TERMS
Molecular Function Cellular Component Biological Process
nucleic acid binding (GO:0003676) RNA-DNA hybrid ribonuclease activity (GO:0004523) serine-type endopeptidase inhibitor activity (GO:0004867) integral component of membrane (GO:0016021) None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
Genome annotation 24807620
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-346 107 - 157 CLQFC 109 - 113 GDEQI 126 - 130 L-H Type (Type-II)
KSCLQFCDNEVAYMTCPSSGDEQISPVCVNCCTADEGCKLFRTDGSLICTG
CLQFC
GDEQI
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K S C L Q F C D N E V A Y M T C P S S G D E Q I S P V C V N C C T A D E G C K L F R T D G S L I C T G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-346
 107 - 157 51
Amino Acid Count % by Frequency
Alanine 9 5.63
Cysteine 10 6.25
Aspartic acid 7 4.38
Glutamic acid 8 5
Phenylalanine 5 3.13
Glycine 14 8.75
Histidine 2 1.25
Isoleucine 11 6.88
Lysine 7 4.38
Leucine 19 11.88
Methionine 5 3.13
Asparagine 6 3.75
Proline 4 2.5
Glutamine 7 4.38
Arginine 6 3.75
Serine 12 7.5
Threonine 10 6.25
Valine 11 6.88
Tryptophan 0 0
Tyrosine 7 4.38