Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_222 [J7EN94]  : Proteinase inhibitor II type B

154Length

Solanum tuberosumSpecie

-Gene Name

16701Mass

4Domain Count

Sequence :
     FASTA
MDVHKEVNFV AYLLIVLGLL VLVSAMEHVD AKACTLECGN LGFGICPRSE GSPENRICTN CCAGYKGCNY 70
YSANGAFICE GESDPKNPNV CPRNCDTNIA YSKCLRSEGK SLIYPTGCTT CCTGYKGCYY FGKNGKFVCE 140
GESDEPKANM YPAM 154
SIGNAL PEPTIDE
SEQUENCE Position
MDVHKEVNFVAYLLIVLGLLVLVSA
 1 ↔ 25
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-237
56 - 107 52
IRD-240
56 - 106 51
IRD-467
32 - 81 50
IRD-489
89 - 141 53
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
5.319
0 -8.8 -14.7
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
J7EN94 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 HM440954
REFERENCES
PubMed ID:    
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 92 - 96
RL-1 CPRNC Trypsin 92 - 96
RL-1 CPRNC Trypsin 92 - 96
RL-9 CTLEC Chymotrypsin 35 - 39
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-237 56 - 107 CPRNC 91 - 95 DPKNP 84 - 88 H-L Type (Type-I)
IRD-240 56 - 106 CPRNC 91 - 95 DPKNP 84 - 88 H-L Type (Type-I)
IRD-467 32 - 81 CTLEC 34 - 38 EGSPE 50 - 54 L-H Type (Type-II)
IRD-489 89 - 141 CPRNC 91 - 95 - H+L Type (Type-III)
RICTNCCAGYKGCNYYSANGAFICEGESDPKNPNVCPRNCDTNIAYSKCLRS
CPRNC
DPKNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G Y K G C N Y Y S A N G A F I C E G E S D P K N P N V C P R N C D T N I A Y S K C L R S


RICTNCCAGYKGCNYYSANGAFICEGESDPKNPNVCPRNCDTNIAYSKCLR
CPRNC
DPKNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
R I C T N C C A G Y K G C N Y Y S A N G A F I C E G E S D P K N P N V C P R N C D T N I A Y S K C L R


KACTLECGNLGFGICPRSEGSPENRICTNCCAGYKGCNYYSANGAFICEG
CTLEC
EGSPE
L-H Type (Type-II)
3,27 ; 7,31 ; 15,37 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K A C T L E C G N L G F G I C P R S E G S P E N R I C T N C C A G Y K G C N Y Y S A N G A F I C E G


NVCPRNCDTNIAYSKCLRSEGKSLIYPTGCTTCCTGYKGCYYFGKNGKFVCEG
CPRNC
H+L Type (Type-III)
3,33 ; 7,34 ; 16,30 ; 40,51
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
N V C P R N C D T N I A Y S K C L R S E G K S L I Y P T G C T T C C T G Y K G C Y Y F G K N G K F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-237
 56 - 107 52
IRD-240
 56 - 106 51
IRD-467
 32 - 81 50
IRD-489
 89 - 141 53
Amino Acid Count % by Frequency
Alanine 10 6.49
Cysteine 16 10.39
Aspartic acid 5 3.25
Glutamic acid 11 7.14
Phenylalanine 5 3.25
Glycine 16 10.39
Histidine 2 1.3
Isoleucine 6 3.9
Lysine 10 6.49
Leucine 10 6.49
Methionine 4 2.6
Asparagine 12 7.79
Proline 8 5.19
Glutamine 0 0
Arginine 4 2.6
Serine 9 5.84
Threonine 7 4.55
Valine 9 5.84
Tryptophan 0 0
Tyrosine 10 6.49