Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_227 [A0A2G2V3L7]  : Proteinase inhibitor type-2

262Length

Capsicum baccatumSpecie

CQW23_32820Gene Name

28475Mass

7Domain Count

Sequence :
     FASTA
MAVPKEVSFL ASLLVLGILL LHVDAKACSQ RNAKEPICTN CCAGRKGCNY YSADGTFICE GESDPNNPKP 70
CTLECDPRIF YSKCPRSEAS AENRICTNCC AGRKGCNYYS ADGTFICEGE SDPNNPKACP RNCDTRIAYS 140
KCPRSEGNAE NRICTNCCAG RKGCNYYSAD GTFVCEGESD PKNPKACTLD CDPRIFYSKC PRSEASAEEP 210
ICTNCCAGRK GCNYYSADGT FVCEGESDPN HPKACPKNCD PNIAYSLCLY EK 262
SIGNAL PEPTIDE
SEQUENCE Position
MAVPKEVSFLASLLVLGILLLHVDA
 1 ↔ 25
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-83
94 - 145 52
IRD-142
36 - 87 52
IRD-144
210 - 261 52
IRD-273
152 - 203 52
IRD-463
69 - 119 51
IRD-477
185 - 235 51
IRD-538
127 - 177 51
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
5.468
0.6 -15.9 -27.7
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
A0A2G2V3L7 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 MLFT02000381
REFERENCES
PubMed ID:     29089032    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 130 - 134
RL-1 CPRNC Trypsin 130 - 134
RL-11 CPKNC Trypsin 246 - 250
RL-31 CTLDC Chymotrypsin 188 - 192
RL-31 CTLDC Chymotrypsin 188 - 192
RL-9 CTLEC Chymotrypsin 72 - 76
RL-9 CTLEC Chymotrypsin 72 - 76
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-83 94 - 145 CPRNC 129 - 133 DPNNP 122 - 126 H-L Type (Type-I)
IRD-142 36 - 87 CTLEC 71 - 75 DPNNP 64 - 68 H-L Type (Type-I)
IRD-144 210 - 261 CPKNC 245 - 249 DPNHP 238 - 242 H-L Type (Type-I)
IRD-273 152 - 203 CTLDC 187 - 191 DPKNP 180 - 184 H-L Type (Type-I)
IRD-463 69 - 119 CTLEC 71 - 75 EASAE 88 - 92 L-H Type (Type-II)
IRD-477 185 - 235 CTLDC 187 - 191 EASAE 204 - 208 L-H Type (Type-II)
IRD-538 127 - 177 CPRNC 129 - 133 EGNAE 146 - 150 L-H Type (Type-II)
RICTNCCAGRKGCNYYSADGTFICEGESDPNNPKACPRNCDTRIAYSKCPRS
CPRNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K A C P R N C D T R I A Y S K C P R S


PICTNCCAGRKGCNYYSADGTFICEGESDPNNPKPCTLECDPRIFYSKCPRS
CTLEC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K P C T L E C D P R I F Y S K C P R S


PICTNCCAGRKGCNYYSADGTFVCEGESDPNHPKACPKNCDPNIAYSLCLYE
CPKNC
DPNHP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C T N C C A G R K G C N Y Y S A D G T F V C E G E S D P N H P K A C P K N C D P N I A Y S L C L Y E


RICTNCCAGRKGCNYYSADGTFVCEGESDPKNPKACTLDCDPRIFYSKCPRS
CTLDC
DPKNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D G T F V C E G E S D P K N P K A C T L D C D P R I F Y S K C P R S


KPCTLECDPRIFYSKCPRSEASAENRICTNCCAGRKGCNYYSADGTFICEG
CTLEC
EASAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K P C T L E C D P R I F Y S K C P R S E A S A E N R I C T N C C A G R K G C N Y Y S A D G T F I C E G


KACTLDCDPRIFYSKCPRSEASAEEPICTNCCAGRKGCNYYSADGTFVCEG
CTLDC
EASAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K A C T L D C D P R I F Y S K C P R S E A S A E E P I C T N C C A G R K G C N Y Y S A D G T F V C E G


KACPRNCDTRIAYSKCPRSEGNAENRICTNCCAGRKGCNYYSADGTFVCEG
CPRNC
EGNAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K A C P R N C D T R I A Y S K C P R S E G N A E N R I C T N C C A G R K G C N Y Y S A D G T F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-83
 94 - 145 52
IRD-142
 36 - 87 52
IRD-144
 210 - 261 52
IRD-273
 152 - 203 52
IRD-463
 69 - 119 51
IRD-477
 185 - 235 51
IRD-538
 127 - 177 51
Amino Acid Count % by Frequency
Alanine 23 8.78
Cysteine 33 12.6
Aspartic acid 14 5.34
Glutamic acid 19 7.25
Phenylalanine 7 2.67
Glycine 18 6.87
Histidine 2 0.76
Isoleucine 11 4.2
Lysine 17 6.49
Leucine 11 4.2
Methionine 1 0.38
Asparagine 21 8.02
Proline 20 7.63
Glutamine 1 0.38
Arginine 14 5.34
Serine 20 7.63
Threonine 11 4.2
Valine 6 2.29
Tryptophan 0 0
Tyrosine 13 4.96