Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_232 [Q3S483]  : Proteinase inhibitor II

154Length

Solanum tuberosumSpecie

-Gene Name

16641Mass

3Domain Count

Sequence :
     FASTA
MAVHKEVNFV GYLLIVLGLL VLVSAMEHVD AKACTLECGN LGFGICPRSE GSPENHICTN CCAGYKGCNY 70
YSANGAFICE GQSDPKKPKA CPLNCDPHIA YSKCPRSEGK SLIYPTGCTT CCTGYKGCYY FDKNGKFVCE 140
GESDEPKANM YPAM 154
SIGNAL PEPTIDE
SEQUENCE Position
MAVHKEVNFVGYLLIVLGLLVLVSA
 1 ↔ 25
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-57
56 - 107 52
IRD-466
32 - 81 50
IRD-495
89 - 141 53
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
6.09
2 -7.8 -13.8
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
Q3S483 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 DQ168323
REFERENCES
PubMed ID:    
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-2 CPLNC Chymotrypsin 92 - 96
RL-2 CPLNC Chymotrypsin 92 - 96
RL-9 CTLEC Chymotrypsin 35 - 39
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-57 56 - 107 CPLNC 91 - 95 DPKKP 84 - 88 H-L Type (Type-I)
IRD-466 32 - 81 CTLEC 34 - 38 EGSPE 50 - 54 L-H Type (Type-II)
IRD-495 89 - 141 CPLNC 91 - 95 - H+L Type (Type-III)
HICTNCCAGYKGCNYYSANGAFICEGQSDPKKPKACPLNCDPHIAYSKCPRS
CPLNC
DPKKP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
H I C T N C C A G Y K G C N Y Y S A N G A F I C E G Q S D P K K P K A C P L N C D P H I A Y S K C P R S


KACTLECGNLGFGICPRSEGSPENHICTNCCAGYKGCNYYSANGAFICEG
CTLEC
EGSPE
L-H Type (Type-II)
3,31 ; 7,37 ; 15,27 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K A C T L E C G N L G F G I C P R S E G S P E N H I C T N C C A G Y K G C N Y Y S A N G A F I C E G


KACPLNCDPHIAYSKCPRSEGKSLIYPTGCTTCCTGYKGCYYFDKNGKFVCEG
CPLNC
H+L Type (Type-III)
3,33 ; 7,34 ; 16,30 ; 40,51
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
K A C P L N C D P H I A Y S K C P R S E G K S L I Y P T G C T T C C T G Y K G C Y Y F D K N G K F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-57
 56 - 107 52
IRD-466
 32 - 81 50
IRD-495
 89 - 141 53
Amino Acid Count % by Frequency
Alanine 11 7.14
Cysteine 16 10.39
Aspartic acid 5 3.25
Glutamic acid 10 6.49
Phenylalanine 5 3.25
Glycine 16 10.39
Histidine 4 2.6
Isoleucine 6 3.9
Lysine 12 7.79
Leucine 10 6.49
Methionine 4 2.6
Asparagine 9 5.84
Proline 10 6.49
Glutamine 1 0.65
Arginine 2 1.3
Serine 9 5.84
Threonine 6 3.9
Valine 8 5.19
Tryptophan 0 0
Tyrosine 10 6.49