Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_234 [Q3S493]  : Proteinase inhibitor II

154Length

Solanum tuberosumSpecie

-Gene Name

16728Mass

3Domain Count

Sequence :
     FASTA
MAVHKEVNFV AYLLIVLGIF LLVSVVEHVD AKACTLECGN LGFGICPRLE GSPTNPICIN CCSGYKGCNY 70
YSAFGRFICE GESDPKNPKA CPLNCDTNIA YSRCSRSKGK TLIYPTGCTT CCTGYKGCYY FGKNGKFVCE 140
GESDEPKANM FPAM 154
SIGNAL PEPTIDE
SEQUENCE Position
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-247
56 - 107 52
IRD-417
32 - 81 50
IRD-443
89 - 141 53
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
6.934
3.8 -4.8 -10.7
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
Q3S493 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 DQ168313
REFERENCES
PubMed ID:    
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-2 CPLNC Chymotrypsin 92 - 96
RL-2 CPLNC Chymotrypsin 92 - 96
RL-9 CTLEC Chymotrypsin 35 - 39
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) integral component of membrane (GO:0016021) None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-247 56 - 107 CPLNC 91 - 95 DPKNP 84 - 88 H-L Type (Type-I)
IRD-417 32 - 81 CTLEC 34 - 38 EGSPT 50 - 54 L-H Type (Type-II)
IRD-443 89 - 141 CPLNC 91 - 95 - H+L Type (Type-III)
PICINCCSGYKGCNYYSAFGRFICEGESDPKNPKACPLNCDTNIAYSRCSRS
CPLNC
DPKNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C I N C C S G Y K G C N Y Y S A F G R F I C E G E S D P K N P K A C P L N C D T N I A Y S R C S R S


KACTLECGNLGFGICPRLEGSPTNPICINCCSGYKGCNYYSAFGRFICEG
CTLEC
EGSPT
L-H Type (Type-II)
3,27 ; 7,31 ; 15,37 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K A C T L E C G N L G F G I C P R L E G S P T N P I C I N C C S G Y K G C N Y Y S A F G R F I C E G


KACPLNCDTNIAYSRCSRSKGKTLIYPTGCTTCCTGYKGCYYFGKNGKFVCEG
CPLNC
H+L Type (Type-III)
3,33 ; 7,34 ; 16,30 ; 40,51
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
K A C P L N C D T N I A Y S R C S R S K G K T L I Y P T G C T T C C T G Y K G C Y Y F G K N G K F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-247
 56 - 107 52
IRD-417
 32 - 81 50
IRD-443
 89 - 141 53
Amino Acid Count % by Frequency
Alanine 9 5.84
Cysteine 16 10.39
Aspartic acid 4 2.6
Glutamic acid 9 5.84
Phenylalanine 8 5.19
Glycine 16 10.39
Histidine 2 1.3
Isoleucine 8 5.19
Lysine 11 7.14
Leucine 10 6.49
Methionine 3 1.95
Asparagine 10 6.49
Proline 9 5.84
Glutamine 0 0
Arginine 4 2.6
Serine 9 5.84
Threonine 8 5.19
Valine 9 5.84
Tryptophan 0 0
Tyrosine 9 5.84