Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_35 [A0A2G2V3L6]  : Proteinase inhibitor type-2

199Length

Capsicum baccatumSpecie

CQW23_32819Gene Name

21245Mass

5Domain Count

Sequence :
     FASTA
MAVHKEVSFL GYLLVLGIFL HHVDGKACTR ECGNLGYGIC PRSEGSAEEP ICTNCCAGYK GCKYYSADGT 70
FICEGESDPN NPKACPRNCD PRIAYSKCPR SQGETLIYPT GCTTCCTGYK GCYYFGKDGK FVCEGESTEP 140
KACTLECDPR VAYMTCPSAG LAKIKDVCVN CCTAGEGCKL YGHNGSLLCT GEPQSISTA 199
SIGNAL PEPTIDE
SEQUENCE Position
MAVHKEVSFLGYLLVLGIFLHHVDG
 1 ↔ 25
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-11
110 - 159 50
IRD-119
50 - 101 52
IRD-410
141 - 191 51
IRD-451
26 - 75 50
IRD-517
83 - 135 53
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
5.772
1.3 -12.1 -20.8
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
A0A2G2V3L6 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 MLFT02000381
REFERENCES
PubMed ID:     29089032    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 86 - 90
RL-1 CPRNC Trypsin 86 - 90
RL-4 CTREC Trypsin 29 - 33
RL-9 CTLEC Chymotrypsin 144 - 148
RL-9 CTLEC Chymotrypsin 144 - 148
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-11 110 - 159 CTLEC 143 - 147 - H+L Type (Type-III)
IRD-119 50 - 101 CPRNC 85 - 89 DPNNP 78 - 82 H-L Type (Type-I)
IRD-410 141 - 191 CTLEC 143 - 147 GLAKI 160 - 164 L-H Type (Type-II)
IRD-451 26 - 75 CTREC 28 - 32 EGSAE 44 - 48 L-H Type (Type-II)
IRD-517 83 - 135 CPRNC 85 - 89 QGETL 102 - 106 L-H Type (Type-II)
TGCTTCCTGYKGCYYFGKDGKFVCEGESTEPKACTLECDPRVAYMTCPSA
CTLEC
H+L Type (Type-III)
3,38 ; 6,24 ; 7,34 ; 13,47
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
T G C T T C C T G Y K G C Y Y F G K D G K F V C E G E S T E P K A C T L E C D P R V A Y M T C P S A


PICTNCCAGYKGCKYYSADGTFICEGESDPNNPKACPRNCDPRIAYSKCPRS
CPRNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
P I C T N C C A G Y K G C K Y Y S A D G T F I C E G E S D P N N P K A C P R N C D P R I A Y S K C P R S


KACTLECDPRVAYMTCPSAGLAKIKDVCVNCCTAGEGCKLYGHNGSLLCTG
CTLEC
GLAKI
L-H Type (Type-II)
3,32 ; 7,38 ; 16,28 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K A C T L E C D P R V A Y M T C P S A G L A K I K D V C V N C C T A G E G C K L Y G H N G S L L C T G


KACTRECGNLGYGICPRSEGSAEEPICTNCCAGYKGCKYYSADGTFICEG
CTREC
EGSAE
L-H Type (Type-II)
3,27 ; 7,31 ; 15,37 ; 30,48
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
K A C T R E C G N L G Y G I C P R S E G S A E E P I C T N C C A G Y K G C K Y Y S A D G T F I C E G


KACPRNCDPRIAYSKCPRSQGETLIYPTGCTTCCTGYKGCYYFGKDGKFVCEG
CPRNC
QGETL
L-H Type (Type-II)
3,33 ; 7,34 ; 16,30 ; 40,51
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
K A C P R N C D P R I A Y S K C P R S Q G E T L I Y P T G C T T C C T G Y K G C Y Y F G K D G K F V C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-11
 110 - 159 50
IRD-119
 50 - 101 52
IRD-410
 141 - 191 51
IRD-451
 26 - 75 50
IRD-517
 83 - 135 53
Amino Acid Count % by Frequency
Alanine 13 6.53
Cysteine 24 12.06
Aspartic acid 7 3.52
Glutamic acid 14 7.04
Phenylalanine 5 2.51
Glycine 24 12.06
Histidine 4 2.01
Isoleucine 8 4.02
Lysine 13 6.53
Leucine 12 6.03
Methionine 2 1.01
Asparagine 7 3.52
Proline 12 6.03
Glutamine 2 1.01
Arginine 6 3.02
Serine 12 6.03
Threonine 14 7.04
Valine 8 4.02
Tryptophan 0 0
Tyrosine 12 6.03