PINIR_352 [D2CH22]  : Pin-II type proteinse inhibitor 23

133Length

Capsicum annuumSpecie

-Gene Name

14597Mass

3Domain Count

Sequence :
    FASTA
MAVPKEVSFL AFLLVLEENA ENRLCTNCCA GRKGCNYYSA DGTFICEGES DPNNPKACPR NCDTRIAYSK 70
CPRSEGNAEN RLCTNCCAGR KGCNYYSADG TFICEGESDP NNPKACPRNC DPNIAYSLCL YEK 133
SIGNAL PEPTIDE
SEQUENCE Position
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
81 - 132 52
23 - 74 52
56 - 106 51
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
4.792
-1.2 -8.7 -14.4
CROSS REFERENCES
REFERENCES
PubMed ID:    
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 59 - 63
RL-1 CPRNC Trypsin 59 - 63
RL-1 CPRNC Trypsin 117 - 121
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
Fruits Helicoverpa armigera Inhibition of 70% of the gut proteinase activity of Helicoverpa armigera,Larval and pupal growth reduction 17870253
leaves Helicoverpa armigera Transgenic expression in tomato plant;IRD-9 and -12 exhibited strong inhibition (70–90%) of trypsin, chymotrypsin and HGP, while IRD-7 (40–70%) showed comparatively less inhibition 23261428
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-84 81 - 132 CPRNC 116 - 120 DPNNP 109 - 113 H-L Type (Type-I)
IRD-90 23 - 74 CPRNC 58 - 62 DPNNP 51 - 55 H-L Type (Type-I)
IRD-536 56 - 106 CPRNC 58 - 62 EGNAE 75 - 79 L-H Type (Type-II)

RLCTNCCAGRKGCNYYSADGTFICEGESDPNNPKACPRNCDPNIAYSLCLYE
CPRNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R L C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K A C P R N C D P N I A Y S L C L Y E



RLCTNCCAGRKGCNYYSADGTFICEGESDPNNPKACPRNCDTRIAYSKCPRS
CPRNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R L C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K A C P R N C D T R I A Y S K C P R S



KACPRNCDTRIAYSKCPRSEGNAENRLCTNCCAGRKGCNYYSADGTFICEG
CPRNC
EGNAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K A C P R N C D T R I A Y S K C P R S E G N A E N R L C T N C C A G R K G C N Y Y S A D G T F I C E G



DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-84
81 - 132 52
IRD-90
23 - 74 52
IRD-536
56 - 106 51
Amino Acid Count % by Frequency
Alanine 12 9.02
Cysteine 16 12.03
Aspartic acid 6 4.51
Glutamic acid 11 8.27
Phenylalanine 4 3.01
Glycine 9 6.77
Histidine 0 0
Isoleucine 4 3.01
Lysine 7 5.26
Leucine 8 6.02
Methionine 1 0.75
Asparagine 15 11.28
Proline 9 6.77
Glutamine 0 0
Arginine 8 6.02
Serine 8 6.02
Threonine 5 3.76
Valine 3 2.26
Tryptophan 0 0
Tyrosine 7 5.26