PINIR_372 [T1PZJ7]  : Pin-II type proteinase inhibitor 37

204Length

Capsicum annuumSpecie

-Gene Name

22437Mass

5Domain Count

Sequence :
    FASTA
MAVPKEVSFL AFVLVLGILL LHVDAKACSE ENAENRICTN CCAGRKGCNY YSADGTFICE GESDPNNPKP 70
CTLNCDPRIF YSKYPRSEGN AENRICTNCC AGRKGCYYYS DDGTFICEGE SDPNNPKPCP RNCDTRIAYS 140
ICPRSEGNAE NRICTNCCAG RKGCNYYSAD GTFICEGESD PNNPKACPRD CDPNIAYSLC LYEK 204
SIGNAL PEPTIDE
SEQUENCE Position
MAVPKEVSFLAFVLVLGILLLHVDA
1 ↔ 25
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
94 - 145 52
36 - 87 52
152 - 203 52
127 - 177 51
69 - 119 51
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
4.63
-3.2 -15.1 -23.6
CROSS REFERENCES
REFERENCES
PubMed ID:    
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 130 - 134
RL-1 CPRNC Trypsin 130 - 134
RL-3 CTLNC Chymotrypsin 72 - 76
RL-3 CTLNC Chymotrypsin 72 - 76
RL-43 CPRDC Trypsin 188 - 192
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
Flowers,stems,fruit,leaves Wounding Insect Oral secretion 23153298
leaves Helicoverpa armigera Transgenic expression in tomato plant;IRD-9 and -12 exhibited strong inhibition (70–90%) of trypsin, chymotrypsin and HGP, while IRD-7 (40–70%) showed comparatively less inhibition 23261428
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-103 94 - 145 CPRNC 129 - 133 DPNNP 122 - 126 H-L Type (Type-I)
IRD-127 36 - 87 CTLNC 71 - 75 DPNNP 64 - 68 H-L Type (Type-I)
IRD-149 152 - 203 CPRDC 187 - 191 DPNNP 180 - 184 H-L Type (Type-I)
IRD-541 127 - 177 CPRNC 129 - 133 EGNAE 146 - 150 L-H Type (Type-II)
IRD-555 69 - 119 CTLNC 71 - 75 EGNAE 88 - 92 L-H Type (Type-II)

RICTNCCAGRKGCYYYSDDGTFICEGESDPNNPKPCPRNCDTRIAYSICPRS
CPRNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C Y Y Y S D D G T F I C E G E S D P N N P K P C P R N C D T R I A Y S I C P R S



RICTNCCAGRKGCNYYSADGTFICEGESDPNNPKPCTLNCDPRIFYSKYPRS
CTLNC
DPNNP
H-L Type (Type-I)
3,24 ; 7,13 ; 36,40
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K P C T L N C D P R I F Y S K Y P R S



RICTNCCAGRKGCNYYSADGTFICEGESDPNNPKACPRDCDPNIAYSLCLYE
CPRDC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K A C P R D C D P N I A Y S L C L Y E



KPCPRNCDTRIAYSICPRSEGNAENRICTNCCAGRKGCNYYSADGTFICEG
CPRNC
EGNAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K P C P R N C D T R I A Y S I C P R S E G N A E N R I C T N C C A G R K G C N Y Y S A D G T F I C E G



KPCTLNCDPRIFYSKYPRSEGNAENRICTNCCAGRKGCYYYSDDGTFICEG
CTLNC
EGNAE
L-H Type (Type-II)
3,32 ; 7,38 ; 28,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K P C T L N C D P R I F Y S K Y P R S E G N A E N R I C T N C C A G R K G C Y Y Y S D D G T F I C E G



DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-103
94 - 145 52
IRD-127
36 - 87 52
IRD-149
152 - 203 52
IRD-541
127 - 177 51
IRD-555
69 - 119 51
Amino Acid Count % by Frequency
Alanine 15 7.35
Cysteine 24 11.76
Aspartic acid 12 5.88
Glutamic acid 15 7.35
Phenylalanine 6 2.94
Glycine 15 7.35
Histidine 1 0.49
Isoleucine 11 5.39
Lysine 10 4.9
Leucine 9 4.41
Methionine 1 0.49
Asparagine 20 9.8
Proline 15 7.35
Glutamine 0 0
Arginine 12 5.88
Serine 13 6.37
Threonine 8 3.92
Valine 5 2.45
Tryptophan 0 0
Tyrosine 12 5.88