Proteins
  2. Proteins (PIs)
  3. Proteins details
PINIR_42 [A0A2G3A0U2]  : Proteinase inhibitor type-2

205Length

Capsicum annuumSpecie

T459_09950Gene Name

22545Mass

5Domain Count

Sequence :
     FASTA
MAVHKEVSFL AFLLVLGILL LHVDAKACSE ENAENRICTN CCAGRKGCNY YSADGTFICE GESDPNNPKA 70
CPRYCDTRIA YSKXKACSEE NAENRICTNC CAGRKGCNYY SADRTFICEG ESDPNNPKAC PRNCDTRIAY 140
SKCPRSEGNA ENRLCTNCCA GRKGCNYYSA DGTFICEGES DPNNPKACPR NCDPNIAYSL CLYEK 205
SIGNAL PEPTIDE
SEQUENCE Position
MAVHKEVSFLAFLLVLGILLLHVDA
 1 ↔ 25
DOMAINS ARCHITECTURE  
Domain Position Length Architecture
IRD-84
153 - 204 52
IRD-109
95 - 146 52
IRD-141
36 - 87 52
IRD-528
69 - 120 52
IRD-536
128 - 178 51
ISO - ELECTRIC POINT
Iso Eelectric Point charge at pH 7.4 charge at pH 5.5 charge at pH 8.0
5.821
1.4 -11.5 -20.5
CROSS REFERENCES
Uniprot Interpro Id Pfam Id EMBL
A0A2G3A0U2 View PI in InterPro
IPR003465 		View protein in Pfam
PF02428		 AYRZ02000003
REFERENCES
PubMed ID:     29089032    |
Application:
REACTIVE LOOPS
Entry RCL Sequence Target Protease Position
RL-1 CPRNC Trypsin 131 - 135
RL-1 CPRNC Trypsin 131 - 135
RL-1 CPRNC Trypsin 189 - 193
RL-6 CPRYC Trypsin 72 - 76
GO TERMS
Molecular Function Cellular Component Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867) None None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution Induction Elicitor Molecules Target Insect Remarks Reference
No Records Found
BIO-CHEMICAL PROPERTIES
Ki (uM) IC50 (uM) Target Protease Cross Reactivity Remarks Reference
No Records Found
BIO-PHYSICAL PROPERTIES
Affinity Binding Energy Stability Remarks Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers Alpha Helix Numbers Coil Numbers Disulphide Bonds Numbers Remarks Reference
No Records Found
Entry Domain Position RCL RCL Position Linker Linker Position Domain Type
IRD-84 153 - 204 CPRNC 188 - 192 DPNNP 181 - 185 H-L Type (Type-I)
IRD-109 95 - 146 CPRNC 130 - 134 DPNNP 123 - 127 H-L Type (Type-I)
IRD-141 36 - 87 CPRYC 71 - 75 DPNNP 64 - 68 H-L Type (Type-I)
IRD-528 69 - 120 CPRYC 71 - 75 EENAE 89 - 93 L-H Type (Type-II)
IRD-536 128 - 178 CPRNC 130 - 134 EGNAE 147 - 151 L-H Type (Type-II)
RLCTNCCAGRKGCNYYSADGTFICEGESDPNNPKACPRNCDPNIAYSLCLYE
CPRNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R L C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K A C P R N C D P N I A Y S L C L Y E


RICTNCCAGRKGCNYYSADRTFICEGESDPNNPKACPRNCDTRIAYSKCPRS
CPRNC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D R T F I C E G E S D P N N P K A C P R N C D T R I A Y S K C P R S


RICTNCCAGRKGCNYYSADGTFICEGESDPNNPKACPRYCDTRIAYSKXKAC
CPRYC
DPNNP
H-L Type (Type-I)
3,40 ; 6,24 ; 7,36 ; 13,52
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
R I C T N C C A G R K G C N Y Y S A D G T F I C E G E S D P N N P K A C P R Y C D T R I A Y S K X K A C


KACPRYCDTRIAYSKXKACSEENAENRICTNCCAGRKGCNYYSADRTFICEG
CPRYC
EENAE
L-H Type (Type-II)
3,29 ; 7,33 ; 19,39 ; 32,50
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
K A C P R Y C D T R I A Y S K X K A C S E E N A E N R I C T N C C A G R K G C N Y Y S A D R T F I C E G


KACPRNCDTRIAYSKCPRSEGNAENRLCTNCCAGRKGCNYYSADGTFICEG
CPRNC
EGNAE
L-H Type (Type-II)
3,28 ; 7,32 ; 16,38 ; 31,49
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
K A C P R N C D T R I A Y S K C P R S E G N A E N R L C T N C C A G R K G C N Y Y S A D G T F I C E G


DOMAINS ARCHITECTURE
Domain Position Length Architecture
IRD-84
 153 - 204 52
IRD-109
 95 - 146 52
IRD-141
 36 - 87 52
IRD-528
 69 - 120 52
IRD-536
 128 - 178 51
Amino Acid Count % by Frequency
Alanine 20 9.76
Cysteine 25 12.2
Aspartic acid 10 4.88
Glutamic acid 16 7.8
Phenylalanine 5 2.44
Glycine 13 6.34
Histidine 2 0.98
Isoleucine 9 4.39
Lysine 12 5.85
Leucine 10 4.88
Methionine 1 0.49
Asparagine 21 10.24
Proline 11 5.37
Glutamine 0 0
Arginine 13 6.34
Serine 13 6.34
Threonine 8 3.9
Valine 4 1.95
Tryptophan 0 0
Tyrosine 11 5.37