Home
Browse
Proteins (PIs)
Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
Taxonomy
Domain Architecture
Data Analysis
Proteins (PIs)
Domains (IRDs)
Reactive Loops (RCL)
Linkers
Target Protease
Search
Downloads
Contact Us
Proteins
Proteins (PIs)
Proteins details
PINIR_5
[
P83241
] :
Proteinase inhibitor PSI-1.2
52
Length
Capsicum annuum
Specie
-
Gene Name
5604
Mass
1
Domain Count
Overview
Function
Domains
Amino acid (aa) Composition
Visualization
Sequence :
FASTA Sequence copied to clipboard!
×
FASTA
KACPRNCDTD
IAYMVCPSSG
ERIIRKVCTN
CCAAQKGCKL
FRSNGSIKCT
GT
52
SIGNAL PEPTIDE
SEQUENCE
Position
DISULPHIDE BOND
Disulfidebondtype
Position
Disulfide bond 1
3 ↔ 31
Disulfide bond 2
7 ↔ 32
Disulfide bond 3
16 ↔ 28
Disulfide bond 4
38 ↔ 49
DOMAINS ARCHITECTURE
View diagram
Domain
Position
Length
Architecture
IRD-491
1 - 51
51
ISO - ELECTRIC POINT
Iso Eelectric Point
charge at pH 7.4
charge at pH 5.5
charge at pH 8.0
8.22299999999999
6.1
2.6
-0.4
CROSS REFERENCES
Uniprot
Interpro Id
Pfam Id
EMBL
P83241
View PI in InterPro
IPR003465
View protein in Pfam
PF02428
REFERENCES
PubMed ID:
11604534
|
Application:
Potent inhibitor of trypsin and a weaker inhibitor of chymotrypsin. It does not inhibit elastase and subtilisin DY. {ECO:0000269|PubMed:11604534}.
REACTIVE LOOPS
Entry
RCL Sequence
Target Protease
Position
RL-1
CPRNC
Trypsin
4 - 8
GO TERMS
Molecular Function
Cellular Component
Biological Process
serine-type endopeptidase inhibitor activity (GO:0004867)
None
None
SPATIO TEMPORAL DISTRIBUTION
Tissue Distribution
Induction
Elicitor Molecules
Target Insect
Remarks
Reference
Seeds
11604534
BIO-CHEMICAL PROPERTIES
Ki (uM)
IC50 (uM)
Target Protease
Cross Reactivity
Remarks
Reference
trypsin (0.046), chymotrypsin (0.11), Thrombin (1.1), Factor Xa (260)
Trypsin
Trypsin, chymotrypsin, thrombin, Factor Xa
11604534
BIO-PHYSICAL PROPERTIES
Affinity
Binding Energy
Stability
Remarks
Reference
No Records Found
DOMAIN STRUCTURE FOLD
Beta Sheet Numbers
Alpha Helix Numbers
Coil Numbers
Disulphide Bonds Numbers
Remarks
Reference
4
11604534
Entry
Domain Position
RCL
RCL Position
Linker
Linker Position
Domain Type
IRD-491
1 - 51
CPRNC
3 - 7
-
H+L Type (Type-III)
Domain(
IRD-491
)
:
KA
CPRNC
DTDIAYMVCPSSGERIIRKVCTNCCAAQKGCKLFRSNGSIKCTG
Reactive Loop(RCL)
:
CPRNC
Linker
:
Domain Type
:
H+L Type (Type-III)
Disulphide Bond
:
3,31 ; 7,32 ; 16,28 ; 38,49
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
K
A
C
P
R
N
C
D
T
D
I
A
Y
M
V
C
P
S
S
G
E
R
I
I
R
K
V
C
T
N
C
C
A
A
Q
K
G
C
K
L
F
R
S
N
G
S
I
K
C
T
G
DOMAINS ARCHITECTURE
Domain
Position
Length
Architecture
IRD-491
1 - 51
51
Amino Acid
Count
% by Frequency
Alanine
4
7.69
Cysteine
8
15.38
Aspartic acid
2
3.85
Glutamic acid
1
1.92
Phenylalanine
1
1.92
Glycine
4
7.69
Histidine
0
0
Isoleucine
4
7.69
Lysine
5
9.62
Leucine
1
1.92
Methionine
1
1.92
Asparagine
3
5.77
Proline
2
3.85
Glutamine
1
1.92
Arginine
4
7.69
Serine
4
7.69
Threonine
4
7.69
Valine
2
3.85
Tryptophan
0
0
Tyrosine
1
1.92
Architecture
×
Domains
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
K
A
C
P
R
N
C
D
T
D
I
A
Y
M
V
C
P
S
S
G
E
R
I
I
R
K
V
C
T
N
C
C
A
A
Q
K
G
C
K
L
F
R
S
N
G
S
I
K
C
T
G
T